Solid-liquid extraction of gallic acid from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves

Labisia Pumila or known as Kacip Fatimah is one of medicinal plants which are rich of bioresource for traditional systems of medicine, food supplements and pharmaceutical intermedtiates. According to scientific researches, the leaf of this plant is proven to posses many beneficial bioactivities and...

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Main Author:	Awang, Mohd Azrie
Format:	Thesis
Language:	English
Published:	2014
Subjects:	Medicinal plants Herbs - Therapeutic use
Online Access:	http://psasir.upm.edu.my/id/eprint/64343/1/FK%202014%20126IR.pdf
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id	my-upm-ir.64343
record_format	uketd_dc
spelling	my-upm-ir.643432018-06-11T07:30:54Z Solid-liquid extraction of gallic acid from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves 2014-08 Awang, Mohd Azrie Labisia Pumila or known as Kacip Fatimah is one of medicinal plants which are rich of bioresource for traditional systems of medicine, food supplements and pharmaceutical intermedtiates. According to scientific researches, the leaf of this plant is proven to posses many beneficial bioactivities and its leaf extract has great potential to be used in developing naturally occurring commercial products in market demand. However, very little research has been carried out with regards to the processing of bioactive extract of L. pumila leaves.This research studied a solidliquid extraction (SLE) process which involved processing of the bioactive extract from L. pumila leaves. Experiments were carried out to determine the effects of various operating parameters on the qualitative and quantitative aspects of L. pumila leaves. Gallic acid (GA) was selected as the quality indicators of the product because this compound played a major role in the bioactivities including anti-inflammatory, antioxidant activity, anti-microbial, anti-cancer and prevention of osteoporosis. Water was found to be most suitable solvent for extracting gallic acid from L. pumila leaves compared to other organic solvents. It gave the highest extraction yield as well as quality extract of GA. It also showed the highest antioxidant and antiinflammatory. The optimum extraction condition of L. pumila leaves were determined as 80°C and the ratio of water to solid is 30:1 (ml:g) based on analysis using Response Surface Methodology (RSM) technique. An equilibrium driven solid liquid extraction (EDSLE) model was developed and successfully applied in describing the process. Medicinal plants Herbs - Therapeutic use 2014-08 Thesis http://psasir.upm.edu.my/id/eprint/64343/ http://psasir.upm.edu.my/id/eprint/64343/1/FK%202014%20126IR.pdf text en public masters Universiti Putra Malaysia Medicinal plants Herbs - Therapeutic use
institution	Universiti Putra Malaysia
collection	PSAS Institutional Repository
language	English
topic	Medicinal plants Herbs - Therapeutic use
spellingShingle	Medicinal plants Herbs - Therapeutic use Awang, Mohd Azrie Solid-liquid extraction of gallic acid from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
description	Labisia Pumila or known as Kacip Fatimah is one of medicinal plants which are rich of bioresource for traditional systems of medicine, food supplements and pharmaceutical intermedtiates. According to scientific researches, the leaf of this plant is proven to posses many beneficial bioactivities and its leaf extract has great potential to be used in developing naturally occurring commercial products in market demand. However, very little research has been carried out with regards to the processing of bioactive extract of L. pumila leaves.This research studied a solidliquid extraction (SLE) process which involved processing of the bioactive extract from L. pumila leaves. Experiments were carried out to determine the effects of various operating parameters on the qualitative and quantitative aspects of L. pumila leaves. Gallic acid (GA) was selected as the quality indicators of the product because this compound played a major role in the bioactivities including anti-inflammatory, antioxidant activity, anti-microbial, anti-cancer and prevention of osteoporosis. Water was found to be most suitable solvent for extracting gallic acid from L. pumila leaves compared to other organic solvents. It gave the highest extraction yield as well as quality extract of GA. It also showed the highest antioxidant and antiinflammatory. The optimum extraction condition of L. pumila leaves were determined as 80°C and the ratio of water to solid is 30:1 (ml:g) based on analysis using Response Surface Methodology (RSM) technique. An equilibrium driven solid liquid extraction (EDSLE) model was developed and successfully applied in describing the process.
format	Thesis
qualification_level	Master's degree
author	Awang, Mohd Azrie
author_facet	Awang, Mohd Azrie
author_sort	Awang, Mohd Azrie
title	Solid-liquid extraction of gallic acid from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title_short	Solid-liquid extraction of gallic acid from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title_full	Solid-liquid extraction of gallic acid from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title_fullStr	Solid-liquid extraction of gallic acid from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title_full_unstemmed	Solid-liquid extraction of gallic acid from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves
title_sort	solid-liquid extraction of gallic acid from kacip fatimah (labisia pumila benth. & hook. f.) leaves
granting_institution	Universiti Putra Malaysia
publishDate	2014
url	http://psasir.upm.edu.my/id/eprint/64343/1/FK%202014%20126IR.pdf
_version_	1747812293013405696

Solid-liquid extraction of gallic acid from Kacip Fatimah (Labisia pumila Benth. & Hook. f.) leaves

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