Agreement between various measurements of standardised uptake value normalised by lean body mass in detecting background 18F-FDG activity in PET/CT oncologic imaging
PET/CT Scan is a diagnostic imaging tool predominantly used in oncology cases. Standardised uptake value (SUV) is the widely accepted method to quantitatively assess lesions detected on PET/CT. There is a limitation to the utility of this method, however, as this value becomes falsely reduced in...
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| Main Author: | |
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| Format: | Thesis |
| Language: | English |
| Published: |
2018
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| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/68570/1/FPSK%28M%29%202018%2010%20-%20IR.pdf |
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| Summary: | PET/CT Scan is a diagnostic imaging tool predominantly used in oncology cases.
Standardised uptake value (SUV) is the widely accepted method to quantitatively
assess lesions detected on PET/CT. There is a limitation to the utility of this
method, however, as this value becomes falsely reduced in overweight patients.
Thus, we propose another quantitative method of using Standard Uptake Lean
Body Mass (SUL) which can give a more consistent reading in patients having
extremes of body mass index (BMI) values. As the prevalence of obesity is rising
in this current decade, the utility of SUL becomes more relevant and necessary.
This study correlated SUV and SUL values using the liver as a baseline reference
organ and identified the pattern of distribution across various BMIs. There have
been some studies that assessed the variations of SUV and SUL in obese
subjects, but there have not been any studies that analysed whether there is a
significant difference in SUL in subjects who undergo contrast-enhanced PET/CT.
Interestingly, this study confirmed that SUL reading is consistent even among
overweight patients and the utility of contrast media in PET/CT scans does not
significantly differ from low dose non-contrast-enhanced scans. |
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