Agreement between various measurements of standardised uptake value normalised by lean body mass in detecting background 18F-FDG activity in PET/CT oncologic imaging

PET/CT Scan is a diagnostic imaging tool predominantly used in oncology cases. Standardised uptake value (SUV) is the widely accepted method to quantitatively assess lesions detected on PET/CT. There is a limitation to the utility of this method, however, as this value becomes falsely reduced in...

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Main Author:	Mohad Azmi, Nur Hafizah
Format:	Thesis
Language:	English
Published:	2018
Subjects:	Body composition Body mass index
Online Access:	http://psasir.upm.edu.my/id/eprint/68570/1/FPSK%28M%29%202018%2010%20-%20IR.pdf
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spelling	my-upm-ir.685702019-05-16T06:38:42Z Agreement between various measurements of standardised uptake value normalised by lean body mass in detecting background 18F-FDG activity in PET/CT oncologic imaging 2018-03 Mohad Azmi, Nur Hafizah PET/CT Scan is a diagnostic imaging tool predominantly used in oncology cases. Standardised uptake value (SUV) is the widely accepted method to quantitatively assess lesions detected on PET/CT. There is a limitation to the utility of this method, however, as this value becomes falsely reduced in overweight patients. Thus, we propose another quantitative method of using Standard Uptake Lean Body Mass (SUL) which can give a more consistent reading in patients having extremes of body mass index (BMI) values. As the prevalence of obesity is rising in this current decade, the utility of SUL becomes more relevant and necessary. This study correlated SUV and SUL values using the liver as a baseline reference organ and identified the pattern of distribution across various BMIs. There have been some studies that assessed the variations of SUV and SUL in obese subjects, but there have not been any studies that analysed whether there is a significant difference in SUL in subjects who undergo contrast-enhanced PET/CT. Interestingly, this study confirmed that SUL reading is consistent even among overweight patients and the utility of contrast media in PET/CT scans does not significantly differ from low dose non-contrast-enhanced scans. Body composition Body mass index 2018-03 Thesis http://psasir.upm.edu.my/id/eprint/68570/ http://psasir.upm.edu.my/id/eprint/68570/1/FPSK%28M%29%202018%2010%20-%20IR.pdf text en public masters Universiti Putra Malaysia Body composition Body mass index
institution	Universiti Putra Malaysia
collection	PSAS Institutional Repository
language	English
topic	Body composition Body mass index
spellingShingle	Body composition Body mass index Mohad Azmi, Nur Hafizah Agreement between various measurements of standardised uptake value normalised by lean body mass in detecting background 18F-FDG activity in PET/CT oncologic imaging
description	PET/CT Scan is a diagnostic imaging tool predominantly used in oncology cases. Standardised uptake value (SUV) is the widely accepted method to quantitatively assess lesions detected on PET/CT. There is a limitation to the utility of this method, however, as this value becomes falsely reduced in overweight patients. Thus, we propose another quantitative method of using Standard Uptake Lean Body Mass (SUL) which can give a more consistent reading in patients having extremes of body mass index (BMI) values. As the prevalence of obesity is rising in this current decade, the utility of SUL becomes more relevant and necessary. This study correlated SUV and SUL values using the liver as a baseline reference organ and identified the pattern of distribution across various BMIs. There have been some studies that assessed the variations of SUV and SUL in obese subjects, but there have not been any studies that analysed whether there is a significant difference in SUL in subjects who undergo contrast-enhanced PET/CT. Interestingly, this study confirmed that SUL reading is consistent even among overweight patients and the utility of contrast media in PET/CT scans does not significantly differ from low dose non-contrast-enhanced scans.
format	Thesis
qualification_level	Master's degree
author	Mohad Azmi, Nur Hafizah
author_facet	Mohad Azmi, Nur Hafizah
author_sort	Mohad Azmi, Nur Hafizah
title	Agreement between various measurements of standardised uptake value normalised by lean body mass in detecting background 18F-FDG activity in PET/CT oncologic imaging
title_short	Agreement between various measurements of standardised uptake value normalised by lean body mass in detecting background 18F-FDG activity in PET/CT oncologic imaging
title_full	Agreement between various measurements of standardised uptake value normalised by lean body mass in detecting background 18F-FDG activity in PET/CT oncologic imaging
title_fullStr	Agreement between various measurements of standardised uptake value normalised by lean body mass in detecting background 18F-FDG activity in PET/CT oncologic imaging
title_full_unstemmed	Agreement between various measurements of standardised uptake value normalised by lean body mass in detecting background 18F-FDG activity in PET/CT oncologic imaging
title_sort	agreement between various measurements of standardised uptake value normalised by lean body mass in detecting background 18f-fdg activity in pet/ct oncologic imaging
granting_institution	Universiti Putra Malaysia
publishDate	2018
url	http://psasir.upm.edu.my/id/eprint/68570/1/FPSK%28M%29%202018%2010%20-%20IR.pdf
_version_	1747812597366784000

Agreement between various measurements of standardised uptake value normalised by lean body mass in detecting background 18F-FDG activity in PET/CT oncologic imaging

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