Effects of different porcine reproductive and respiratory syndrome vaccine regimes on pig immunity status in selected pig farms in Malaysia

Vaccination is a key component of PRRS disease control strategies. Various types of vaccines, including killed virus (KV) and modified-live virus (MLV) vaccines had been develop for the control of the disease. In Malaysia field condition, the producers adopted different vaccination regime which e...

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Main Author:	Cheah, Zi Herk
Format:	Thesis
Language:	English
Published:	2019
Subjects:	Animal Diseases - immunology Veterinary immunology
Online Access:	http://psasir.upm.edu.my/id/eprint/84520/1/FPV%202019%208%20ir.pdf
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spelling	my-upm-ir.845202022-01-03T02:44:59Z Effects of different porcine reproductive and respiratory syndrome vaccine regimes on pig immunity status in selected pig farms in Malaysia 2019-05 Cheah, Zi Herk Vaccination is a key component of PRRS disease control strategies. Various types of vaccines, including killed virus (KV) and modified-live virus (MLV) vaccines had been develop for the control of the disease. In Malaysia field condition, the producers adopted different vaccination regime which either breeder vaccination only or whole herd (both breeder and porker herd) vaccination regime. Therefore, the ideal vaccines option (strain or type) and vaccination approach had remained highly debatable in the market. Thus, the objective of this study is to determine the pig immunity status against PRRS in farm by comparing different farms which practicing different vaccination regime or different types of PRRS vaccines in Malaysia farm condition by using PCR and ELISA technique to check on the vertical and horizontal disease transmission and disease pressure in the farm. There are 4 vaccinations regime being include in this study where Farm A only vaccinated Type 2 MLV in breeder herd, Farm B vaccinated both Breeder and porkers with Type 2 MLV, Farm C only vaccinated Type 1 killed vaccine (KV) in Breeder herd and Farm D vaccinated both Breeder and porker with type 1 MLV. All samples collected from all farms were test with both PCR and ELISA. Results showed that whole herd vaccinating MLV approach is a better option for PRRSv control in the farm compare to breeder approach (Chapter 3). In the farm that practiced whole herd vaccination approach, Type 2 MLV showed its benefit in establishing the dominant strain in the farm and able to better control of PRRSv circulation in the farm as compare to Type 1 MLV (Chapter 4). When comparing between Type 2 MLV and Type 1 KV in breeder herd vaccination approach (Chapter 5), the study showed that Type 2 MLV demonstrated its benefit in controlling PRRSv shedding in the herd over Type 1 KV. The conclusion obtain from this research to combat PRRS by strategically practice whole herd vaccination regime (Chapter 3), using the Type 2 (US strain) vaccine strain (Chapter 4) and MLV type vaccine (Chapter 5). Animal Diseases - immunology Veterinary immunology 2019-05 Thesis http://psasir.upm.edu.my/id/eprint/84520/ http://psasir.upm.edu.my/id/eprint/84520/1/FPV%202019%208%20ir.pdf text en public masters Universiti Putra Malaysia Animal Diseases - immunology Veterinary immunology Ooi, Peck Toung
institution	Universiti Putra Malaysia
collection	PSAS Institutional Repository
language	English
advisor	Ooi, Peck Toung
topic	Animal Diseases - immunology Veterinary immunology
spellingShingle	Animal Diseases - immunology Veterinary immunology Cheah, Zi Herk Effects of different porcine reproductive and respiratory syndrome vaccine regimes on pig immunity status in selected pig farms in Malaysia
description	Vaccination is a key component of PRRS disease control strategies. Various types of vaccines, including killed virus (KV) and modified-live virus (MLV) vaccines had been develop for the control of the disease. In Malaysia field condition, the producers adopted different vaccination regime which either breeder vaccination only or whole herd (both breeder and porker herd) vaccination regime. Therefore, the ideal vaccines option (strain or type) and vaccination approach had remained highly debatable in the market. Thus, the objective of this study is to determine the pig immunity status against PRRS in farm by comparing different farms which practicing different vaccination regime or different types of PRRS vaccines in Malaysia farm condition by using PCR and ELISA technique to check on the vertical and horizontal disease transmission and disease pressure in the farm. There are 4 vaccinations regime being include in this study where Farm A only vaccinated Type 2 MLV in breeder herd, Farm B vaccinated both Breeder and porkers with Type 2 MLV, Farm C only vaccinated Type 1 killed vaccine (KV) in Breeder herd and Farm D vaccinated both Breeder and porker with type 1 MLV. All samples collected from all farms were test with both PCR and ELISA. Results showed that whole herd vaccinating MLV approach is a better option for PRRSv control in the farm compare to breeder approach (Chapter 3). In the farm that practiced whole herd vaccination approach, Type 2 MLV showed its benefit in establishing the dominant strain in the farm and able to better control of PRRSv circulation in the farm as compare to Type 1 MLV (Chapter 4). When comparing between Type 2 MLV and Type 1 KV in breeder herd vaccination approach (Chapter 5), the study showed that Type 2 MLV demonstrated its benefit in controlling PRRSv shedding in the herd over Type 1 KV. The conclusion obtain from this research to combat PRRS by strategically practice whole herd vaccination regime (Chapter 3), using the Type 2 (US strain) vaccine strain (Chapter 4) and MLV type vaccine (Chapter 5).
format	Thesis
qualification_level	Master's degree
author	Cheah, Zi Herk
author_facet	Cheah, Zi Herk
author_sort	Cheah, Zi Herk
title	Effects of different porcine reproductive and respiratory syndrome vaccine regimes on pig immunity status in selected pig farms in Malaysia
title_short	Effects of different porcine reproductive and respiratory syndrome vaccine regimes on pig immunity status in selected pig farms in Malaysia
title_full	Effects of different porcine reproductive and respiratory syndrome vaccine regimes on pig immunity status in selected pig farms in Malaysia
title_fullStr	Effects of different porcine reproductive and respiratory syndrome vaccine regimes on pig immunity status in selected pig farms in Malaysia
title_full_unstemmed	Effects of different porcine reproductive and respiratory syndrome vaccine regimes on pig immunity status in selected pig farms in Malaysia
title_sort	effects of different porcine reproductive and respiratory syndrome vaccine regimes on pig immunity status in selected pig farms in malaysia
granting_institution	Universiti Putra Malaysia
publishDate	2019
url	http://psasir.upm.edu.my/id/eprint/84520/1/FPV%202019%208%20ir.pdf
_version_	1747813483543527424

Effects of different porcine reproductive and respiratory syndrome vaccine regimes on pig immunity status in selected pig farms in Malaysia

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