Chemical Constituents of Glycosmis Calcicola and G. Rupestris (Rutaceae) and Their Biological Activities

Investigation of the leaf and tvig sex tracts of Glycosm is calcicola (Rutaceae) from two different locations has led to the isolation of five compounds. The structures of the secompounds were elucidated by means of spectroscopic methods(IR, uv, ¹H-NMR, ¹³C- NMR, MS)and by comparison with previ...

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Main Author: Chew, Yean Ling
Format: Thesis
Language:English
English
Published: 1995
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Online Access:http://psasir.upm.edu.my/id/eprint/8599/1/FSAS_1995_7_A.pdf
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spelling my-upm-ir.85992018-10-26T17:14:56Z Chemical Constituents of Glycosmis Calcicola and G. Rupestris (Rutaceae) and Their Biological Activities 1995 Chew, Yean Ling Investigation of the leaf and tvig sex tracts of Glycosm is calcicola (Rutaceae) from two different locations has led to the isolation of five compounds. The structures of the secompounds were elucidated by means of spectroscopic methods(IR, uv, ¹H-NMR, ¹³C- NMR, MS)and by comparison with previous studies. G. calcicola collected from Langk aviIsl and yielded ethyl gerambullin Isitosterol and another unidentified compound .From another separate collection of the same plant from Templer Park, a new alkaloid (desmethoxyzanthophylline)and f1indersine have also been isolated. A similar study on the bark of another species, G. rupestris, collected from Langkawi Island afforded methoxyglycomaurin), a new alkaloid (7-glycomaurin, des-Nmethylacronycine and stigmast-7-enol, while the leaves of the plant gave an unidentified compound. The antifungal activities of these plant extracts were evaluated using the poison food and spore germination techniques. The plant extracts exhibited varying degree of fungitoxic response on the growth of the fungal pathogens of chilli (Capsicum annuum L.). The chloroform extract of G. calcicola collected from Templer Park has been shown to be most effective in inhibiting the mycelial growth, sporulation and spore germination of Chaonephora cucurbi tarium, Col1etotrichum capsici and C. gloeosporioides. The antifungal compounds in this extract were identified using TLC bioassay technique against Aspergillus flavus. The results indicated that the activity of the extract is due to the presence of its major components: flindersine and desmethoxyzanthophylline. Rutaceae Chemical elements 1995 Thesis http://psasir.upm.edu.my/id/eprint/8599/ http://psasir.upm.edu.my/id/eprint/8599/1/FSAS_1995_7_A.pdf application/pdf en public masters Universiti Pertanian Malaysia Rutaceae Chemical elements Faculty of Environmental Studies English
institution Universiti Putra Malaysia
collection PSAS Institutional Repository
language English
English
topic Rutaceae
Chemical elements

spellingShingle Rutaceae
Chemical elements

Chew, Yean Ling
Chemical Constituents of Glycosmis Calcicola and G. Rupestris (Rutaceae) and Their Biological Activities
description Investigation of the leaf and tvig sex tracts of Glycosm is calcicola (Rutaceae) from two different locations has led to the isolation of five compounds. The structures of the secompounds were elucidated by means of spectroscopic methods(IR, uv, ¹H-NMR, ¹³C- NMR, MS)and by comparison with previous studies. G. calcicola collected from Langk aviIsl and yielded ethyl gerambullin Isitosterol and another unidentified compound .From another separate collection of the same plant from Templer Park, a new alkaloid (desmethoxyzanthophylline)and f1indersine have also been isolated. A similar study on the bark of another species, G. rupestris, collected from Langkawi Island afforded methoxyglycomaurin), a new alkaloid (7-glycomaurin, des-Nmethylacronycine and stigmast-7-enol, while the leaves of the plant gave an unidentified compound. The antifungal activities of these plant extracts were evaluated using the poison food and spore germination techniques. The plant extracts exhibited varying degree of fungitoxic response on the growth of the fungal pathogens of chilli (Capsicum annuum L.). The chloroform extract of G. calcicola collected from Templer Park has been shown to be most effective in inhibiting the mycelial growth, sporulation and spore germination of Chaonephora cucurbi tarium, Col1etotrichum capsici and C. gloeosporioides. The antifungal compounds in this extract were identified using TLC bioassay technique against Aspergillus flavus. The results indicated that the activity of the extract is due to the presence of its major components: flindersine and desmethoxyzanthophylline.
format Thesis
qualification_level Master's degree
author Chew, Yean Ling
author_facet Chew, Yean Ling
author_sort Chew, Yean Ling
title Chemical Constituents of Glycosmis Calcicola and G. Rupestris (Rutaceae) and Their Biological Activities
title_short Chemical Constituents of Glycosmis Calcicola and G. Rupestris (Rutaceae) and Their Biological Activities
title_full Chemical Constituents of Glycosmis Calcicola and G. Rupestris (Rutaceae) and Their Biological Activities
title_fullStr Chemical Constituents of Glycosmis Calcicola and G. Rupestris (Rutaceae) and Their Biological Activities
title_full_unstemmed Chemical Constituents of Glycosmis Calcicola and G. Rupestris (Rutaceae) and Their Biological Activities
title_sort chemical constituents of glycosmis calcicola and g. rupestris (rutaceae) and their biological activities
granting_institution Universiti Pertanian Malaysia
granting_department Faculty of Environmental Studies
publishDate 1995
url http://psasir.upm.edu.my/id/eprint/8599/1/FSAS_1995_7_A.pdf
_version_ 1747810835749666816