Chemical Constituents of Garcinia Mangostana, G. Parvifolla, G. Griffitti and G. Diversifolia (Guttiferae) and Their Biological Activities
Four plants from the Garcinia genus were subjected to chemotaxonomic investigations with the isolation of a number of compounds. The structures of the compounds were established by spectroscopic methods such as MS, UV, IR, 1HNMR and 13C-NMR and by comparison with previous studies. The investigat...
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| Format: | Thesis |
| Language: | English English |
| Published: |
1996
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| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/8608/1/FSAS_1996_6_A.pdf |
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| Summary: | Four plants from the Garcinia genus were subjected to chemotaxonomic
investigations with the isolation of a number of compounds. The structures of the
compounds were established by spectroscopic methods such as MS, UV, IR, 1HNMR
and 13C-NMR and by comparison with previous studies.
The investigations of the pericarp of local grown Garcinia mangostana
afforded known compounds which are mangostin, l3-mangostin, y-mangostin and
gartanin.In investigations of the bark and heartwood of G. parvifolia collected from
Ayer Hitam Forest Reserve, Puchong two xanthones, GP2, GH2 and stigmasterol
were isolated. From another separate collection of the same species from Johor,
three compounds were isolated: stigmasterol, an unidentified compound and an
novel compound, GK3.
Study on the leaves and stems of G. griffitti collected from Taman Negara ,
Pahang afforded two known compounds friedelin and (3-amyrin. Investigations on
leaves and stems of G. diversifolia collected from Fraser's Hill also yielded friede!in.
The plant extracts were evaluated for their biological activities against
selected fungal and bacterial pathogens. The antifungal activity was performed
using the 'Poison Food' method. The extracts from the test plant showed different
antifungal activity towards the vegetative growth of plant pathogenic fungi ;
Helminthosporium oryzae, Alternaria padwickii, Colletotrichum capsici, Fusarium
oxysporum, Curvularia lunata and Pesta/otia theae The chloroform extract of the
heartwood of G. parvifolia collected from Ayer Hitam Forest Reserve, Puchong was
the most effective in inhibiting the mycelial growth for the test fungi.
The antibacterial activity was tested using the 'Agar Diffusion' method. The
extracts from the test plant also showed different antibacterial activity against the
growth of six test bacteria ; Bacillus subtilis, E. coli, Erwinia carotovora,
Microccoccus sp, Proteus vulgariS and Pseudomonas solanacearum. Chloroform
extract of G. mangostana gave the highest average zone of inhibition, indicating the
degree of its sensitivity. |
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