Isolation, Identification and Bioactivity of Natural Products from Melaleuca Cajuputi (Myrtacea)
In this study the components of aerial and subterranean parts of Melaleuca cajuputi were isolated and identified. Chemical investigation on the leaves resulted in the isolation of two known triterpenoids, betulinic acid and u rsolic acid ester. The oily fractions contained two phenolic components...
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| Main Author: | |
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| Format: | Thesis |
| Language: | English English |
| Published: |
1996
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| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/8609/1/FSAS_1996_8_A.pdf |
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| Summary: | In this study the components of aerial and subterranean parts of
Melaleuca cajuputi were isolated and identified. Chemical investigation on
the leaves resulted in the isolation of two known triterpenoids, betulinic acid
and u rsolic acid ester. The oily fractions contained two phenolic components,
a naphthalene dione, an anthracene carboxal-dehyde and a phenenthracene
analogy.
Methanol extracts of the bark, seeds, and flowers allowed for the
isolation and identification of betulinic acid, urolic acid and betuline,
respectively. Their structures were determined using m odern spectroscopic
techniques such as IR, NMR, MS and by comparison with literature.The bioassay was carried out on crude extracts of leaves,
roots, seeds, and bark against first in star mosquito larvae (Aedes albopictus) according to the procedure described in the literature.
These extracts were found to be acute or relatively toxic to the target
organisms. Extract from leaves exhibited the highest toxicity followed
by extracts from roots, seeds, and bark respectively. |
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