Synthesis and biological evaluation of a series of analogues of 2,4,6-trihydroxy-3-geranylacetophenone, an anti-inflammatory natural product compound

The natural product molecule 2,4,6-trihydroxy-3-geranylacetophenone (tHGA) isolated from the medicinal plant Melicope ptelefolia was shown to exhibit potent lipoxygenase (LOX) inhibitory activity. It is known that LOX plays an important role in inflammatory response as it catalyzes the oxidation of...

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主要作者: Ng, Chean Hui
格式: Thesis
语言:English
出版: 2017
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在线阅读:http://psasir.upm.edu.my/id/eprint/92467/1/IB%202017%208%20UPMIR.pdf
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