Studies on coordination chemistry and bioactivity of Cu(II), Cd(II) and Zn(II) complexes containing some nitrogen-sulphur donor ligands
Several Schiff bases of S-benzyldithiocarbazate (SBDTC) and S-methyldithiocarbazate (SMDTC) have been synthesised. Complexes of Cu(II), Cd(II) and Zn(II) with the pyridine-2-carboxaldehyde Schiff base of SBDrC were prepared. The compounds were characterised by elemental analyses and various physi...
Saved in:
| Main Author: | |
|---|---|
| Format: | Thesis |
| Language: | English English |
| Published: |
2001
|
| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/9248/1/FSAS_2001_22.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | Several Schiff bases of S-benzyldithiocarbazate (SBDTC) and S-methyldithiocarbazate
(SMDTC) have been synthesised. Complexes of Cu(II), Cd(II) and Zn(II) with the
pyridine-2-carboxaldehyde Schiff base of SBDrC were prepared. The compounds were
characterised by elemental analyses and various physico-chemical techniques. The
Schiff bases and the metal complexes were tested for cytotoxicity and antimicrobial and
antioxidant activities. Cytotoxic screenings were carried out against T-lymphoblastic
leukaemia cells (CEM-SS) and colon cancer cells (HI -29). The antimicrobial
screenings were carried out against four bacteria and four fungi. The antioxidative
assay was carried out using the ferric thiocyanate (FTC) method. The Cu(II) and Cd(II)
complexes were four coordinate while the Zn(II) complex was six coordinate. |
|---|