Production and Properties of Polysaccharides from Mycelia of Three Ganoderma Species
Phannacological research has shown that extract of certain Ganoderma species have medical effects including anti-tumor, anti-virus, lowering blood fat and regulating blood pressure. One of the major ingredients of the water extract of Ganoderma fruit bodies is the polysaccharides and these are t...
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| Format: | Thesis |
| Language: | English English |
| Published: |
1999
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| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/9486/1/FSAS_1999_28_A.pdf |
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| Summary: | Phannacological research has shown that extract of certain
Ganoderma species have medical effects including anti-tumor, anti-virus,
lowering blood fat and regulating blood pressure.
One of the major ingredients of the water extract of Ganoderma
fruit bodies is the polysaccharides and these are the polysaccharides which
have been studied more extensively. However, new findings have
recommended producing the Ganoderma mycelium instead of the fruiting
bodies because of the several advantages in producing the fungal
mycelium. Thus, this project was focused on the production and properties
of polysaccharides from the Ganoderma mycelium. Mycelia of three Ganoderma species (G. luddum, G. tropicum and
G. tsugae) were inoculated into five types of liquid growth media (barley
extract, Fergus media, Mizuno media, PDB and soya bean extract) for 15
days at 25°C. Among these media tested, soya bean extract supported good
growth of the fungal mycelium of all the three species of Ganoderma.
Increasing the soya bean concentration resulted in a gradual increase in the
growth of the fungal mycelium as well as the amount of the
polysaccharides produced. Yield of total carbohydrates produced by the
mycelium in all the three species reached its maximum level when
incubated at 25°C for 15 days. A whole range of different polysaccharides
with different molecular weights and linkage types were obtained from the
culture filtrate, homogenized mycelium fraction as well as the hot water
extraction of mycelium harvested at different periods of incubation.
Polysaccharide with B-(1,3) linkages that were reported to have
pharmaceutical value were identified. These polysaccharides were found
to have a common molecular weight of 27,000 Da. |
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