Exploring neuronal activation in response to reward through fMRI correlated with simultaneous EEG among male undergraduates having problematic smartphone usage

Smartphone usage among young Malaysian adults has increased dramatically in the past decade leading to smartphone addiction (SPA) particularly involving social networking applications such as Instagram. SPA prevalence has been noted to be as high as 47% among medical students in a Malaysian unive...

Full description

Saved in:

Bibliographic Details
Main Author:	Hamed, Sharifat
Format:	Thesis
Language:	English
Published:	2020
Subjects:	Magnetic Resonance Imaging Diagnostic imaging Electroencephalography
Online Access:	http://psasir.upm.edu.my/id/eprint/99192/1/FPSK%28M%29%202021%2028%20IR.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-upm-ir.99192
record_format	uketd_dc
spelling	my-upm-ir.991922023-03-06T06:54:25Z Exploring neuronal activation in response to reward through fMRI correlated with simultaneous EEG among male undergraduates having problematic smartphone usage 2020-08 Hamed, Sharifat Smartphone usage among young Malaysian adults has increased dramatically in the past decade leading to smartphone addiction (SPA) particularly involving social networking applications such as Instagram. SPA prevalence has been noted to be as high as 47% among medical students in a Malaysian university. There is a need to objectively assess the cerebral mechanisms that respond to reward using electroencephalography (EEG)-informed functional magnetic resonance imaging (fMRI) also known as EEG-fMRI as a potential biomarker. Therefore, after receiving ethical clearance, an observational study was conducted among 24 male UPM students using Smartphone Addiction Scale- Malay version (SAS-M) questionnaire, modified Instagram Addiction Scale (IAS) and EEG-fMRI. The subjects were recruited by simple random sampling from a Phase 1 cross sectional study comprising of 850 male UPM students who had been administered with the SAS-M questionnaire. Subjects with SAS-M scores ≥ 98 and IAS ≥ 37 were considered High scorers (HS) and deemed to be having SPA, whereas subjects with SAS-M scores < 98 and IAS < 37 were considered Low Scorers (LS) and deemed as healthy controls. A 64-channel EEG scalp electrode was placed on the participants (12 HS, 12 LS) and a task-based fMRI was performed with simultaneous EEG recordings. Evoked response potential (ERP) derivatives of EEG namely the P300 peak waves and contingent negativity variance (CNV) were analyzed using Brain- Vision EEG analyzer and fMRI dataset were analyzed using Statistical Parametric Mapping (SPM). There was significant difference in the P300 wave amplitude between HS and LS, which corresponded well with cerebral activations regions related to response to reward. The combination of the high spatial resolution of fMRI with the high temporal resolution of EEG to correlate cerebral regional activation, in response to cue related reactivity during response to reward task among smartphone addicts, has the potential to be a surrogate biological marker for assessment of Instagram addiction. Magnetic Resonance Imaging Diagnostic imaging Electroencephalography 2020-08 Thesis http://psasir.upm.edu.my/id/eprint/99192/ http://psasir.upm.edu.my/id/eprint/99192/1/FPSK%28M%29%202021%2028%20IR.pdf text en public masters Universiti Putra Malaysia Magnetic Resonance Imaging Diagnostic imaging Electroencephalography Suppiah, Subapriya
institution	Universiti Putra Malaysia
collection	PSAS Institutional Repository
language	English
advisor	Suppiah, Subapriya
topic	Magnetic Resonance Imaging Diagnostic imaging Electroencephalography
spellingShingle	Magnetic Resonance Imaging Diagnostic imaging Electroencephalography Hamed, Sharifat Exploring neuronal activation in response to reward through fMRI correlated with simultaneous EEG among male undergraduates having problematic smartphone usage
description	Smartphone usage among young Malaysian adults has increased dramatically in the past decade leading to smartphone addiction (SPA) particularly involving social networking applications such as Instagram. SPA prevalence has been noted to be as high as 47% among medical students in a Malaysian university. There is a need to objectively assess the cerebral mechanisms that respond to reward using electroencephalography (EEG)-informed functional magnetic resonance imaging (fMRI) also known as EEG-fMRI as a potential biomarker. Therefore, after receiving ethical clearance, an observational study was conducted among 24 male UPM students using Smartphone Addiction Scale- Malay version (SAS-M) questionnaire, modified Instagram Addiction Scale (IAS) and EEG-fMRI. The subjects were recruited by simple random sampling from a Phase 1 cross sectional study comprising of 850 male UPM students who had been administered with the SAS-M questionnaire. Subjects with SAS-M scores ≥ 98 and IAS ≥ 37 were considered High scorers (HS) and deemed to be having SPA, whereas subjects with SAS-M scores < 98 and IAS < 37 were considered Low Scorers (LS) and deemed as healthy controls. A 64-channel EEG scalp electrode was placed on the participants (12 HS, 12 LS) and a task-based fMRI was performed with simultaneous EEG recordings. Evoked response potential (ERP) derivatives of EEG namely the P300 peak waves and contingent negativity variance (CNV) were analyzed using Brain- Vision EEG analyzer and fMRI dataset were analyzed using Statistical Parametric Mapping (SPM). There was significant difference in the P300 wave amplitude between HS and LS, which corresponded well with cerebral activations regions related to response to reward. The combination of the high spatial resolution of fMRI with the high temporal resolution of EEG to correlate cerebral regional activation, in response to cue related reactivity during response to reward task among smartphone addicts, has the potential to be a surrogate biological marker for assessment of Instagram addiction.
format	Thesis
qualification_level	Master's degree
author	Hamed, Sharifat
author_facet	Hamed, Sharifat
author_sort	Hamed, Sharifat
title	Exploring neuronal activation in response to reward through fMRI correlated with simultaneous EEG among male undergraduates having problematic smartphone usage
title_short	Exploring neuronal activation in response to reward through fMRI correlated with simultaneous EEG among male undergraduates having problematic smartphone usage
title_full	Exploring neuronal activation in response to reward through fMRI correlated with simultaneous EEG among male undergraduates having problematic smartphone usage
title_fullStr	Exploring neuronal activation in response to reward through fMRI correlated with simultaneous EEG among male undergraduates having problematic smartphone usage
title_full_unstemmed	Exploring neuronal activation in response to reward through fMRI correlated with simultaneous EEG among male undergraduates having problematic smartphone usage
title_sort	exploring neuronal activation in response to reward through fmri correlated with simultaneous eeg among male undergraduates having problematic smartphone usage
granting_institution	Universiti Putra Malaysia
publishDate	2020
url	http://psasir.upm.edu.my/id/eprint/99192/1/FPSK%28M%29%202021%2028%20IR.pdf
_version_	1776100302152269824

Exploring neuronal activation in response to reward through fMRI correlated with simultaneous EEG among male undergraduates having problematic smartphone usage

Similar Items