Analysis Of Genetic Association Of TGFΒ1 And SMAD4 Genes With Keloid In Malay Population

Keloid is a complex condition with environmental and genetic risk-contributing factors. Two candidate genes, TGFβ1 and SMAD4, located in the same signaling pathway are highly expressed in the keloid fibroblast cells. The present study investigated the association between variants of TGFβ1 and SMA...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Azadeh, Emami
التنسيق: أطروحة
اللغة:English
منشور في: 2012
الموضوعات:
الوصول للمادة أونلاين:http://eprints.usm.my/28963/1/ANALYSIS_OF_GENETIC_ASSOCIATION_OF_TGFB1_AND_SMAD4_GENES_WITH_KELOID_IN_MALAY_POPULATION.pdf
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spelling my-usm-ep.289632019-04-12T05:26:24Z Analysis Of Genetic Association Of TGFΒ1 And SMAD4 Genes With Keloid In Malay Population 2012 Azadeh, Emami R5-130.5 General works Keloid is a complex condition with environmental and genetic risk-contributing factors. Two candidate genes, TGFβ1 and SMAD4, located in the same signaling pathway are highly expressed in the keloid fibroblast cells. The present study investigated the association between variants of TGFβ1 and SMAD4 genes using PCR-RFLP genotyping method. Pembentukkan keloid adalah sebabkan oleh faktor persekitaran and genetik. Dua jenis gen iaitu TGFβ1 dan SMAD4 yang terletak pada signal yang sama dan sangat tinggi di ekpresi di dalam fibroblast sel keloid. Kajian ini bertujuan untuk menyiasat kaitan di antara varian TGFβ1 dan SMAD4 gen menggunakan kaedah genotyping PCR-RFLP. 2012 Thesis http://eprints.usm.my/28963/ http://eprints.usm.my/28963/1/ANALYSIS_OF_GENETIC_ASSOCIATION_OF_TGFB1_AND_SMAD4_GENES_WITH_KELOID_IN_MALAY_POPULATION.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R5-130.5 General works
spellingShingle R5-130.5 General works
Azadeh, Emami
Analysis Of Genetic Association Of TGFΒ1 And SMAD4 Genes With Keloid In Malay Population
description Keloid is a complex condition with environmental and genetic risk-contributing factors. Two candidate genes, TGFβ1 and SMAD4, located in the same signaling pathway are highly expressed in the keloid fibroblast cells. The present study investigated the association between variants of TGFβ1 and SMAD4 genes using PCR-RFLP genotyping method. Pembentukkan keloid adalah sebabkan oleh faktor persekitaran and genetik. Dua jenis gen iaitu TGFβ1 dan SMAD4 yang terletak pada signal yang sama dan sangat tinggi di ekpresi di dalam fibroblast sel keloid. Kajian ini bertujuan untuk menyiasat kaitan di antara varian TGFβ1 dan SMAD4 gen menggunakan kaedah genotyping PCR-RFLP.
format Thesis
qualification_level Master's degree
author Azadeh, Emami
author_facet Azadeh, Emami
author_sort Azadeh, Emami
title Analysis Of Genetic Association Of TGFΒ1 And SMAD4 Genes With Keloid In Malay Population
title_short Analysis Of Genetic Association Of TGFΒ1 And SMAD4 Genes With Keloid In Malay Population
title_full Analysis Of Genetic Association Of TGFΒ1 And SMAD4 Genes With Keloid In Malay Population
title_fullStr Analysis Of Genetic Association Of TGFΒ1 And SMAD4 Genes With Keloid In Malay Population
title_full_unstemmed Analysis Of Genetic Association Of TGFΒ1 And SMAD4 Genes With Keloid In Malay Population
title_sort analysis of genetic association of tgfβ1 and smad4 genes with keloid in malay population
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Perubatan
publishDate 2012
url http://eprints.usm.my/28963/1/ANALYSIS_OF_GENETIC_ASSOCIATION_OF_TGFB1_AND_SMAD4_GENES_WITH_KELOID_IN_MALAY_POPULATION.pdf
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