Molecular Cloning, Expression, And Characterization Of Glutathione-Stransferase As A Novel Target In Antimalarial Drug Design And Discovery
Glutation-S-transferase (GSTs) adalah sekumpulan enzim detoksifikasi. Plasmodium falciparum mempunyai isoform tunggal GST (PfGST) yang terlibat dalam bagi detoksifikasi heme. The Glutathione-S-transferases (GSTs) are group of detoxification enzymes. Plasmodium falciparum has a single isoform o...
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Main Author: | |
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Format: | Thesis |
Language: | English |
Published: |
2015
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Subjects: | |
Online Access: | http://eprints.usm.my/30219/1/PhD_thesis_Mohammed_Nooraldeen_Mahmod_march_2015.pdf |
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Summary: | Glutation-S-transferase (GSTs) adalah sekumpulan enzim detoksifikasi. Plasmodium
falciparum mempunyai isoform tunggal GST (PfGST) yang terlibat dalam bagi
detoksifikasi heme.
The Glutathione-S-transferases (GSTs) are group of detoxification enzymes.
Plasmodium falciparum has a single isoform of GST (PfGST) that involves in heme
detoxification. While other GSTs isoforms from human (hGSTP1) and mouse
(mGSTM1) are involved in apoptotic stress kinase pathway and mediate cancer cell
resistance to chemotherapy. |
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