Perkembangan Kaedah Pra-Klinlkal Asid Artesunik, Satu Terbitan Artemisinin Yang Baru
Artesunic acid, a derivative of artemisinin has proven to be rapidly effective and safe in the treatment of malaria. Artesunic acid has been formulated for parenteral and oral use and has recently become available as suppositories for rectal administration. Artesunic acid and it's active met...
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my-usm-ep.305922016-09-28T01:39:17Z Perkembangan Kaedah Pra-Klinlkal Asid Artesunik, Satu Terbitan Artemisinin Yang Baru 2002-04 V. Sathasivam, Kathiresan R5-920 Medicine (General) Artesunic acid, a derivative of artemisinin has proven to be rapidly effective and safe in the treatment of malaria. Artesunic acid has been formulated for parenteral and oral use and has recently become available as suppositories for rectal administration. Artesunic acid and it's active metabolite, dihydroartemisinin used in all these studies was characterized using infrared and nuclear magnetic resonance. The purity was determined by high performance liquid chromatography coupled with an electrochemical detector. Asid artesunik merupakan terbitan artemisinin yang berkesan dan selamat digunakan untuk merawat kes-kes malaria. Asid artesunik wluud dalam formulasi parenteral dan oral, kini dibentuk secara suppositori untuk pemberian secara rektal. Sehingga kini, masih tiada kaedah pelarutan secara rasmi bagi suppositori asid artesunik. Kaedah inframerah dan resonans magnetik nuklear telah digunakan untuk pencirian asid artesunik dan metobolit aktifnya, dihidroartemisinin.. Ketulenan sebatian-sebatian tersebut telah ditentukan menggunakan kromatografi cecair prestasi tinggi yang dilengkapi dengan pengesan elektrokimia. 2002-04 Thesis http://eprints.usm.my/30592/ http://eprints.usm.my/30592/1/KATHIRESAN_A.L_V.SATHASIVAM.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Penyelidikan Dadah & Ubat-ubatan |
| institution |
Universiti Sains Malaysia |
| collection |
USM Institutional Repository |
| language |
English |
| topic |
R5-920 Medicine (General) |
| spellingShingle |
R5-920 Medicine (General) V. Sathasivam, Kathiresan Perkembangan Kaedah Pra-Klinlkal Asid Artesunik, Satu Terbitan Artemisinin Yang Baru |
| description |
Artesunic acid, a derivative of artemisinin has proven to be rapidly effective and safe in the
treatment of malaria. Artesunic acid has been formulated for parenteral and oral use and
has recently become available as suppositories for rectal administration. Artesunic acid and
it's active metabolite, dihydroartemisinin used in all these studies was characterized using
infrared and nuclear magnetic resonance. The purity was determined by high performance
liquid chromatography coupled with an electrochemical detector.
Asid artesunik merupakan terbitan artemisinin yang berkesan dan selamat digunakan
untuk merawat kes-kes malaria. Asid artesunik wluud dalam formulasi parenteral dan
oral, kini dibentuk secara suppositori untuk pemberian secara rektal. Sehingga kini, masih
tiada kaedah pelarutan secara rasmi bagi suppositori asid artesunik. Kaedah inframerah
dan resonans magnetik nuklear telah digunakan untuk pencirian asid artesunik dan
metobolit aktifnya, dihidroartemisinin.. Ketulenan sebatian-sebatian tersebut telah
ditentukan menggunakan kromatografi cecair prestasi tinggi yang dilengkapi dengan
pengesan elektrokimia. |
| format |
Thesis |
| qualification_level |
Master's degree |
| author |
V. Sathasivam, Kathiresan |
| author_facet |
V. Sathasivam, Kathiresan |
| author_sort |
V. Sathasivam, Kathiresan |
| title |
Perkembangan Kaedah Pra-Klinlkal Asid Artesunik,
Satu Terbitan Artemisinin Yang Baru
|
| title_short |
Perkembangan Kaedah Pra-Klinlkal Asid Artesunik,
Satu Terbitan Artemisinin Yang Baru
|
| title_full |
Perkembangan Kaedah Pra-Klinlkal Asid Artesunik,
Satu Terbitan Artemisinin Yang Baru
|
| title_fullStr |
Perkembangan Kaedah Pra-Klinlkal Asid Artesunik,
Satu Terbitan Artemisinin Yang Baru
|
| title_full_unstemmed |
Perkembangan Kaedah Pra-Klinlkal Asid Artesunik,
Satu Terbitan Artemisinin Yang Baru
|
| title_sort |
perkembangan kaedah pra-klinlkal asid artesunik,
satu terbitan artemisinin yang baru |
| granting_institution |
Universiti Sains Malaysia |
| granting_department |
Pusat Penyelidikan Dadah & Ubat-ubatan |
| publishDate |
2002 |
| url |
http://eprints.usm.my/30592/1/KATHIRESAN_A.L_V.SATHASIVAM.pdf |
| _version_ |
1747820364327550976 |