Pulsed Magnetic Stimulation In The Treatment Of Stress Urinary Incontinence In Female Subjects

Stimulasi magnetik terdenyut (PMS) telah digunakan sebagai pilihan rawatan tanpa bedah untuk menangani masalah inkontinens urinari jenis stres (SUI) sejak tahun 1999 disebabkan faktor keselamatan, tidak invasif, dan prosedur rawatan yang mudah. Namun demikian, 'Fifth International Consultati...

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Main Author:	Lim, Renly
Format:	Thesis
Language:	English
Published:	2016
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/32191/1/LIM_RENLY_24%28NN%29.pdf
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id	my-usm-ep.32191
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spelling	my-usm-ep.321912019-04-12T05:25:21Z Pulsed Magnetic Stimulation In The Treatment Of Stress Urinary Incontinence In Female Subjects 2016-04 Lim, Renly RS1-441 Pharmacy and materia medica Stimulasi magnetik terdenyut (PMS) telah digunakan sebagai pilihan rawatan tanpa bedah untuk menangani masalah inkontinens urinari jenis stres (SUI) sejak tahun 1999 disebabkan faktor keselamatan, tidak invasif, dan prosedur rawatan yang mudah. Namun demikian, 'Fifth International Consultation on Incontinence' menekankan bahawa bukti kajian yang sedia ada adalah tidak mencukupi untuk membimbing sebarang cadangan tentang penggunaannya untuk menangani masalah inkontinens urinari, dan kajian klinikal terkawal yang berkualiti tinggi adalah diperlukan. Oleh yang demikian, kajian ini bertujuan menilai keberkesanan PMS untuk rawatan masalah inkontinens urinari. Sebelum kajian di atas dilaksanakan, kajian sistematik telah dijalankan untuk menilai bukti PMS yang sedia ada dalam rawatan pesakit yang didiagnosis mengalami masalah inkontinens urinari. Hasil kajian menunjukkan bahawa PMS mengurangkan simptom masalah inkontinens urinari dalam kalangan wanita untuk jangka masa pendek. Walau bagaimanapun, tanpa kajian klinikal berkualiti tinggi, kesesuaian PMS sebagai pilihan rawatan untuk menangani masalah inkontinens urinari masih diragui. Oleh itu, protokol kajian klinikal yang berkualiti tinggi direka untuk menangani batasan-batasan yang diperhatikan. Pulsed magnetic stimulation (PMS) has been used as a non-surgical option for stress urinary incontinence (SUI) since 1999 due to its established safety, noninvasiveness and simplicity of treatment procedures. However, the Fifth International Consultation on Incontinence (ICI) emphasised that the current evidence is insufficient to guide any recommendation on its use for urinary incontinence, and that well-powered randomised controlled trials are needed. Hence, the present study aimed to evaluate the efficacy of PMS for SUI in a randomized, double-blind, shamcontrolled trial. Prior to the above study, a systematic review was conducted to appraise existing evidence on PMS for patients with urinary incontinence. The results showed that PMS provided short-term improvement for incontinence symptoms in women. However, in the absence of high quality trials, the applicability of PMS as a treatment option for urinary incontinence remained uncertain. Thus, a high-quality clinical trial protocol was designed to address the key limitations noted. 2016-04 Thesis http://eprints.usm.my/32191/ http://eprints.usm.my/32191/1/LIM_RENLY_24%28NN%29.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Farmasi (School of Pharmaceutical Sciences)
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Lim, Renly Pulsed Magnetic Stimulation In The Treatment Of Stress Urinary Incontinence In Female Subjects
description	Stimulasi magnetik terdenyut (PMS) telah digunakan sebagai pilihan rawatan tanpa bedah untuk menangani masalah inkontinens urinari jenis stres (SUI) sejak tahun 1999 disebabkan faktor keselamatan, tidak invasif, dan prosedur rawatan yang mudah. Namun demikian, 'Fifth International Consultation on Incontinence' menekankan bahawa bukti kajian yang sedia ada adalah tidak mencukupi untuk membimbing sebarang cadangan tentang penggunaannya untuk menangani masalah inkontinens urinari, dan kajian klinikal terkawal yang berkualiti tinggi adalah diperlukan. Oleh yang demikian, kajian ini bertujuan menilai keberkesanan PMS untuk rawatan masalah inkontinens urinari. Sebelum kajian di atas dilaksanakan, kajian sistematik telah dijalankan untuk menilai bukti PMS yang sedia ada dalam rawatan pesakit yang didiagnosis mengalami masalah inkontinens urinari. Hasil kajian menunjukkan bahawa PMS mengurangkan simptom masalah inkontinens urinari dalam kalangan wanita untuk jangka masa pendek. Walau bagaimanapun, tanpa kajian klinikal berkualiti tinggi, kesesuaian PMS sebagai pilihan rawatan untuk menangani masalah inkontinens urinari masih diragui. Oleh itu, protokol kajian klinikal yang berkualiti tinggi direka untuk menangani batasan-batasan yang diperhatikan. Pulsed magnetic stimulation (PMS) has been used as a non-surgical option for stress urinary incontinence (SUI) since 1999 due to its established safety, noninvasiveness and simplicity of treatment procedures. However, the Fifth International Consultation on Incontinence (ICI) emphasised that the current evidence is insufficient to guide any recommendation on its use for urinary incontinence, and that well-powered randomised controlled trials are needed. Hence, the present study aimed to evaluate the efficacy of PMS for SUI in a randomized, double-blind, shamcontrolled trial. Prior to the above study, a systematic review was conducted to appraise existing evidence on PMS for patients with urinary incontinence. The results showed that PMS provided short-term improvement for incontinence symptoms in women. However, in the absence of high quality trials, the applicability of PMS as a treatment option for urinary incontinence remained uncertain. Thus, a high-quality clinical trial protocol was designed to address the key limitations noted.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Lim, Renly
author_facet	Lim, Renly
author_sort	Lim, Renly
title	Pulsed Magnetic Stimulation In The Treatment Of Stress Urinary Incontinence In Female Subjects
title_short	Pulsed Magnetic Stimulation In The Treatment Of Stress Urinary Incontinence In Female Subjects
title_full	Pulsed Magnetic Stimulation In The Treatment Of Stress Urinary Incontinence In Female Subjects
title_fullStr	Pulsed Magnetic Stimulation In The Treatment Of Stress Urinary Incontinence In Female Subjects
title_full_unstemmed	Pulsed Magnetic Stimulation In The Treatment Of Stress Urinary Incontinence In Female Subjects
title_sort	pulsed magnetic stimulation in the treatment of stress urinary incontinence in female subjects
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Farmasi (School of Pharmaceutical Sciences)
publishDate	2016
url	http://eprints.usm.my/32191/1/LIM_RENLY_24%28NN%29.pdf
_version_	1747820540730540032

Pulsed Magnetic Stimulation In The Treatment Of Stress Urinary Incontinence In Female Subjects

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