Investigation On Nasal Airflow Of Malaysian Females Using Cfd

Inabilities of objective measurement methods to obtain various important information regarding human nasal airflow leads to the application of Computational Fluid Dynamics (CFD) to study and analyze the complicated structures of the nasal cavity. This research focuses on detailed investigation of Ma...

Full description

Saved in:

Bibliographic Details
Main Author:	Lee, Chih Fang
Format:	Thesis
Language:	English
Published:	2014
Subjects:	T1-995 Technology(General)
Online Access:	http://eprints.usm.my/36896/1/LEE_CHIH_FANG_24_Pages.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-usm-ep.36896
record_format	uketd_dc
spelling	my-usm-ep.368962019-04-12T05:26:04Z Investigation On Nasal Airflow Of Malaysian Females Using Cfd 2014 Lee, Chih Fang T1-995 Technology(General) Inabilities of objective measurement methods to obtain various important information regarding human nasal airflow leads to the application of Computational Fluid Dynamics (CFD) to study and analyze the complicated structures of the nasal cavity. This research focuses on detailed investigation of Malaysian female nasal cavities which includes mucous effects, standardized model and disease cases. In this study, mucous layer effects on nasal airflow were studied by thickening the mucous layer from 5 to 50 μm and analysis were carried out with mass flow rate ranging from 7.5 to 20 L/min. Analysis results of non-mucous effects were compared with the thickening mucous layer effects. Based on the results obtained, healthy mucous layer thickness within the range of 5 to 30 μm caused insignificant effects towards the total nasal airflow. Unique and distinctive features of the human nasal cavities require generalization of its geometry and thus, this study creates a standardized female Malaysian nasal cavity. The methodology implemented in this research involves simple programming of averaging pixel values from a set of Computational Tomography (CT) scans. Therefore, it is simpler and requires shorter time compared to other method used in previous research. The average velocity magnitudes calculated from the four individual models match closely with the standardized model with a difference of less than 20%. This proves that the generated model can represent an average and standardized model of an adult Malaysian female. Huge differences from the comparisons with the standardized model of different population shows the need for a standardized model which represents different xx population due to the diversity of the human nasal cavities. In addition to that, Particle Image Velocimetry (PIV) experimental work and acoustic rhinometry measurements were carried out for validation purposes. Good agreement between the computational, calculation, experimental and rhinometry measurements results provides a strong validation of the computational analysis conducted in this research. As an initial step towards implementing virtual surgery in the future, this study analyzed the pre-operation and post-operation CT scans of the two female patients with nasal diseases (sinusitis). CFD analysis for pre and post-operation conditions allow better observation of the infected areas as well as the nasal airflow behavior such as velocity magnitudes in order to assist rhinologist to view the effects of the surgeries carried out. The results and observations obtained from this research bring a step forward in advancement of virtual surgery in the future and will be beneficial in clinical research development. 2014 Thesis http://eprints.usm.my/36896/ http://eprints.usm.my/36896/1/LEE_CHIH_FANG_24_Pages.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Kejuruteraan Aeroangkasa
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	T1-995 Technology(General)
spellingShingle	T1-995 Technology(General) Lee, Chih Fang Investigation On Nasal Airflow Of Malaysian Females Using Cfd
description	Inabilities of objective measurement methods to obtain various important information regarding human nasal airflow leads to the application of Computational Fluid Dynamics (CFD) to study and analyze the complicated structures of the nasal cavity. This research focuses on detailed investigation of Malaysian female nasal cavities which includes mucous effects, standardized model and disease cases. In this study, mucous layer effects on nasal airflow were studied by thickening the mucous layer from 5 to 50 μm and analysis were carried out with mass flow rate ranging from 7.5 to 20 L/min. Analysis results of non-mucous effects were compared with the thickening mucous layer effects. Based on the results obtained, healthy mucous layer thickness within the range of 5 to 30 μm caused insignificant effects towards the total nasal airflow. Unique and distinctive features of the human nasal cavities require generalization of its geometry and thus, this study creates a standardized female Malaysian nasal cavity. The methodology implemented in this research involves simple programming of averaging pixel values from a set of Computational Tomography (CT) scans. Therefore, it is simpler and requires shorter time compared to other method used in previous research. The average velocity magnitudes calculated from the four individual models match closely with the standardized model with a difference of less than 20%. This proves that the generated model can represent an average and standardized model of an adult Malaysian female. Huge differences from the comparisons with the standardized model of different population shows the need for a standardized model which represents different xx population due to the diversity of the human nasal cavities. In addition to that, Particle Image Velocimetry (PIV) experimental work and acoustic rhinometry measurements were carried out for validation purposes. Good agreement between the computational, calculation, experimental and rhinometry measurements results provides a strong validation of the computational analysis conducted in this research. As an initial step towards implementing virtual surgery in the future, this study analyzed the pre-operation and post-operation CT scans of the two female patients with nasal diseases (sinusitis). CFD analysis for pre and post-operation conditions allow better observation of the infected areas as well as the nasal airflow behavior such as velocity magnitudes in order to assist rhinologist to view the effects of the surgeries carried out. The results and observations obtained from this research bring a step forward in advancement of virtual surgery in the future and will be beneficial in clinical research development.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Lee, Chih Fang
author_facet	Lee, Chih Fang
author_sort	Lee, Chih Fang
title	Investigation On Nasal Airflow Of Malaysian Females Using Cfd
title_short	Investigation On Nasal Airflow Of Malaysian Females Using Cfd
title_full	Investigation On Nasal Airflow Of Malaysian Females Using Cfd
title_fullStr	Investigation On Nasal Airflow Of Malaysian Females Using Cfd
title_full_unstemmed	Investigation On Nasal Airflow Of Malaysian Females Using Cfd
title_sort	investigation on nasal airflow of malaysian females using cfd
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Kejuruteraan Aeroangkasa
publishDate	2014
url	http://eprints.usm.my/36896/1/LEE_CHIH_FANG_24_Pages.pdf
_version_	1747820650702045184

Investigation On Nasal Airflow Of Malaysian Females Using Cfd

Similar Items