Rapid pleurodesis using small bore pigtail catheter and bleomycin in malignant pleural effusions: a case series

Pleural drainage is the treatment of choice for patients presented with symptomatic malignant pleural effusion. The conventional method of treatment is insertion of large bore thoracostomy tube (chest tube) before proceeding to chemical pleurodesis. The aim of this preliminary prospective study was...

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Main Author:	Md Hashim , Mohd Nizam
Format:	Thesis
Language:	English
Published:	2009
Subjects:	RD Surgery
Online Access:	http://eprints.usm.my/37598/1/Pages_from_Dr._Mohd_Nizam_Md_Hashim.pdf
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id	my-usm-ep.37598
record_format	uketd_dc
spelling	my-usm-ep.375982019-04-12T05:27:00Z Rapid pleurodesis using small bore pigtail catheter and bleomycin in malignant pleural effusions: a case series 2009-05 Md Hashim , Mohd Nizam RD Surgery Pleural drainage is the treatment of choice for patients presented with symptomatic malignant pleural effusion. The conventional method of treatment is insertion of large bore thoracostomy tube (chest tube) before proceeding to chemical pleurodesis. The aim of this preliminary prospective study was to investigate the success rate of performing pleurodesis using a small bore pigtail catheter (Mar Flow® CH12) in patients with malignant pleural effusion. Pleurodesis was performed within twenty four hours after insertion of pigtail catheter with bleomycin as sclerosing agent. Patients were follow-up at four weeks post pleurodesis with chest radiography. The intervention was scored as “successful” if no radiographic evidence of fluid reaccumulation was noted at four weeks. A “partial success” score indicated accumulation of fluid that did not produce symptoms and did not require repeat pleural drainage of any sort. All other outcomes were scored as “unsuccessful”. Five patients with malignant pleural effusion from Hospital Universiti Sains Malaysia and Hospital Raja Perempuan Zainab II were included in this study with mean age of 53.6 year old. The primary diseases include breast, lung, ovarian and colon cancers. The mean time of pleurodesis was 9.5 hours. Of the five pleurodesis performed, a complete response (“successful”) was seen in three patients (60%), a partial response (“partial success”) was seen in one patient (20%) and one patient (20%) did not respond to rapid pleurodesis. In conclusion, pleurodesis in patients with malignant pleurodesis can be achieved rapidly using small bore pigtail catheter and bleomycin. 2009-05 Thesis http://eprints.usm.my/37598/ http://eprints.usm.my/37598/1/Pages_from_Dr._Mohd_Nizam_Md_Hashim.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RD Surgery
spellingShingle	RD Surgery Md Hashim , Mohd Nizam Rapid pleurodesis using small bore pigtail catheter and bleomycin in malignant pleural effusions: a case series
description	Pleural drainage is the treatment of choice for patients presented with symptomatic malignant pleural effusion. The conventional method of treatment is insertion of large bore thoracostomy tube (chest tube) before proceeding to chemical pleurodesis. The aim of this preliminary prospective study was to investigate the success rate of performing pleurodesis using a small bore pigtail catheter (Mar Flow® CH12) in patients with malignant pleural effusion. Pleurodesis was performed within twenty four hours after insertion of pigtail catheter with bleomycin as sclerosing agent. Patients were follow-up at four weeks post pleurodesis with chest radiography. The intervention was scored as “successful” if no radiographic evidence of fluid reaccumulation was noted at four weeks. A “partial success” score indicated accumulation of fluid that did not produce symptoms and did not require repeat pleural drainage of any sort. All other outcomes were scored as “unsuccessful”. Five patients with malignant pleural effusion from Hospital Universiti Sains Malaysia and Hospital Raja Perempuan Zainab II were included in this study with mean age of 53.6 year old. The primary diseases include breast, lung, ovarian and colon cancers. The mean time of pleurodesis was 9.5 hours. Of the five pleurodesis performed, a complete response (“successful”) was seen in three patients (60%), a partial response (“partial success”) was seen in one patient (20%) and one patient (20%) did not respond to rapid pleurodesis. In conclusion, pleurodesis in patients with malignant pleurodesis can be achieved rapidly using small bore pigtail catheter and bleomycin.
format	Thesis
qualification_level	Master's degree
author	Md Hashim , Mohd Nizam
author_facet	Md Hashim , Mohd Nizam
author_sort	Md Hashim , Mohd Nizam
title	Rapid pleurodesis using small bore pigtail catheter and bleomycin in malignant pleural effusions: a case series
title_short	Rapid pleurodesis using small bore pigtail catheter and bleomycin in malignant pleural effusions: a case series
title_full	Rapid pleurodesis using small bore pigtail catheter and bleomycin in malignant pleural effusions: a case series
title_fullStr	Rapid pleurodesis using small bore pigtail catheter and bleomycin in malignant pleural effusions: a case series
title_full_unstemmed	Rapid pleurodesis using small bore pigtail catheter and bleomycin in malignant pleural effusions: a case series
title_sort	rapid pleurodesis using small bore pigtail catheter and bleomycin in malignant pleural effusions: a case series
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2009
url	http://eprints.usm.my/37598/1/Pages_from_Dr._Mohd_Nizam_Md_Hashim.pdf
_version_	1747820670235967488

Rapid pleurodesis using small bore pigtail catheter and bleomycin in malignant pleural effusions: a case series

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