Delayed versus early appendicectomy in adult patients with acute appendicitis: a retrospective study in Hospital Sultanah Nur Zahirah, Terengganu

Introduction: One of the commonest intraabdominal diseases is acute appendicitis and requiring emergency surgery. Delaying appendectomy and treated medically did not show any increasing morbidity. Aim: This study compared the association and outcomes adult patients with acute appendicitis betwee...

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Main Author: Abdullah, Rusli
Format: Thesis
Language:English
Published: 2014
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Online Access:http://eprints.usm.my/39665/1/Dr._Rusli_Abdullah_%28General_Surgery%29-24_pages.pdf
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spelling my-usm-ep.396652019-04-12T05:26:03Z Delayed versus early appendicectomy in adult patients with acute appendicitis: a retrospective study in Hospital Sultanah Nur Zahirah, Terengganu 2014 Abdullah, Rusli RC799-869 Diseases of the digestive system. Gastroenterology Introduction: One of the commonest intraabdominal diseases is acute appendicitis and requiring emergency surgery. Delaying appendectomy and treated medically did not show any increasing morbidity. Aim: This study compared the association and outcomes adult patients with acute appendicitis between delayed appendicectomy and early appendicectomy Method: This is a retrospective study of adult patients with acute appendicitis who underwent appendicectomy between 1st January 2012 and 31st December 2012 in Hospital Sultanah Nur Zahirah, Kuala Terengganu. The patients were divided into two groups according to the time of surgery after admission. The early group underwent appendicectomy done within 24 hours of admission and delayed group appendicectomy after 24 hours. These data included demographic, operative characteristic, clinical presentation, laboratory results, Alvarado score, histopathology result, days of meal, length hospital stay, duration of intravenous antibiotic, duration of the operation and postoperative complications were evaluated and compared. Results: A total of 536 patients in this study but only 436 patients were included in the study. There were 290 patients in the early group and 146 in the delayed group. There were no significant differences in clinical presentation except in rebound tenderness and guarding with highly significant in early group 31.7% (p=0.002) and 19% (p=0.02), respectively. The laboratory result, leukocytosis was highly significant in the early group 79% compared to 67.8% in the delayed group but there was no significant difference in graph shift to the left. The Alvarado score was significantly different between groups which were 48.6% and 37%, respectively in score more than 7. There were no significant differences in histopathology results between two groups. There were significant differences in days started meal, length of hospital stay, duration of intravenous antibiotic and duration of the operation with mean 1.18 days, 2.92 days, 1.97 days and 47.65 minutes, respectively in delayed group (p<0.05). Compared to early group mean 1.07, 2.26, 1.30 and 42.29, respectively. There were no significant differences in postoperative complications. Conclusion: Performing delayed appendicectomy after 24 hours from admission does not increase the complications rate and increase progression of the disease. However, delayed appendicectomy increases the days started meal, length of hospital stay, duration of intravenous antibiotic and duration of the operation. 2014 Thesis http://eprints.usm.my/39665/ http://eprints.usm.my/39665/1/Dr._Rusli_Abdullah_%28General_Surgery%29-24_pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic RC799-869 Diseases of the digestive system
Gastroenterology
spellingShingle RC799-869 Diseases of the digestive system
Gastroenterology
Abdullah, Rusli
Delayed versus early appendicectomy in adult patients with acute appendicitis: a retrospective study in Hospital Sultanah Nur Zahirah, Terengganu
description Introduction: One of the commonest intraabdominal diseases is acute appendicitis and requiring emergency surgery. Delaying appendectomy and treated medically did not show any increasing morbidity. Aim: This study compared the association and outcomes adult patients with acute appendicitis between delayed appendicectomy and early appendicectomy Method: This is a retrospective study of adult patients with acute appendicitis who underwent appendicectomy between 1st January 2012 and 31st December 2012 in Hospital Sultanah Nur Zahirah, Kuala Terengganu. The patients were divided into two groups according to the time of surgery after admission. The early group underwent appendicectomy done within 24 hours of admission and delayed group appendicectomy after 24 hours. These data included demographic, operative characteristic, clinical presentation, laboratory results, Alvarado score, histopathology result, days of meal, length hospital stay, duration of intravenous antibiotic, duration of the operation and postoperative complications were evaluated and compared. Results: A total of 536 patients in this study but only 436 patients were included in the study. There were 290 patients in the early group and 146 in the delayed group. There were no significant differences in clinical presentation except in rebound tenderness and guarding with highly significant in early group 31.7% (p=0.002) and 19% (p=0.02), respectively. The laboratory result, leukocytosis was highly significant in the early group 79% compared to 67.8% in the delayed group but there was no significant difference in graph shift to the left. The Alvarado score was significantly different between groups which were 48.6% and 37%, respectively in score more than 7. There were no significant differences in histopathology results between two groups. There were significant differences in days started meal, length of hospital stay, duration of intravenous antibiotic and duration of the operation with mean 1.18 days, 2.92 days, 1.97 days and 47.65 minutes, respectively in delayed group (p<0.05). Compared to early group mean 1.07, 2.26, 1.30 and 42.29, respectively. There were no significant differences in postoperative complications. Conclusion: Performing delayed appendicectomy after 24 hours from admission does not increase the complications rate and increase progression of the disease. However, delayed appendicectomy increases the days started meal, length of hospital stay, duration of intravenous antibiotic and duration of the operation.
format Thesis
qualification_level Master's degree
author Abdullah, Rusli
author_facet Abdullah, Rusli
author_sort Abdullah, Rusli
title Delayed versus early appendicectomy in adult patients with acute appendicitis: a retrospective study in Hospital Sultanah Nur Zahirah, Terengganu
title_short Delayed versus early appendicectomy in adult patients with acute appendicitis: a retrospective study in Hospital Sultanah Nur Zahirah, Terengganu
title_full Delayed versus early appendicectomy in adult patients with acute appendicitis: a retrospective study in Hospital Sultanah Nur Zahirah, Terengganu
title_fullStr Delayed versus early appendicectomy in adult patients with acute appendicitis: a retrospective study in Hospital Sultanah Nur Zahirah, Terengganu
title_full_unstemmed Delayed versus early appendicectomy in adult patients with acute appendicitis: a retrospective study in Hospital Sultanah Nur Zahirah, Terengganu
title_sort delayed versus early appendicectomy in adult patients with acute appendicitis: a retrospective study in hospital sultanah nur zahirah, terengganu
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Perubatan
publishDate 2014
url http://eprints.usm.my/39665/1/Dr._Rusli_Abdullah_%28General_Surgery%29-24_pages.pdf
_version_ 1747820764269117440