The association of anxiety and mood symptoms in patients with bipolar disorders attending follow-up treatment

Background: Anxiety is common in Bipolar Disorders (BD). It is associated with poorer outcome in BD, for example increased in relapse rate and hospitalization, suicidality, substance abuse and more severe symptoms of mania and depression. Malaysian study regarding anxiety in BD is still lacking....

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Main Author:	Khalil Azizan, Mohammad Nabhan
Format:	Thesis
Language:	English
Published:	2015
Subjects:	RC31-1245 Internal medicine
Online Access:	http://eprints.usm.my/40450/1/Dr._Mohammad_Nabhan_Khalil_Azizan_%28Psychiatry%29-24_pages.pdf
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spelling	my-usm-ep.404502020-03-25T09:44:54Z The association of anxiety and mood symptoms in patients with bipolar disorders attending follow-up treatment 2015 Khalil Azizan, Mohammad Nabhan RC31-1245 Internal medicine Background: Anxiety is common in Bipolar Disorders (BD). It is associated with poorer outcome in BD, for example increased in relapse rate and hospitalization, suicidality, substance abuse and more severe symptoms of mania and depression. Malaysian study regarding anxiety in BD is still lacking. Objective: The aim of this study was to determine prevalence of significant anxiety and its detection rate in psychiatric outpatient clinic. Sociodemographic and clinical characteristics associated with anxiety were also examined. Correlation between anxiety and mood symptoms and the burden of life events within one-year period were measured. Method: This is a cross-sectional study done in psychiatric outpatient clinic in Hospital Universiti Sains Malaysia. Sociodemographic and clinical data were acquired from selected samples and four self-rated scales [Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), Young Mania Rating Scale (YMRS) and Social Readjustment Rating Scale (SRRS)] were administered to measure mood symptoms, anxiety symptoms and the burden of life events within the previous one year. Regression and correlation analysis were done to examine relationship between anxiety symptoms and mood symptoms and sociodemographic and clinical data. Results: 20.5% of the total 132 participants had significant level of anxiety. Among these, only 29.3% were detected by clinicians. Anxiety level (BAI) in BD was positively and independently associated with Bipolar II Disorder, number of relapse and BDI score. There was strong positive correlation between BAI and BDI (r = 0.690, p <0.001). There was weak positive correlation between BAI and SRRS (r = 0.194, p =0.026). Conclusion: Anxiety in BD is poorly detected by clinicians and was associated with Bipolar II Disorder, higher frequency of relapse, more severe depression, and more burdens of life event within one-year period. Clinicians need to be sensitive in detecting anxiety in BD. More research is needed in finding effective treatment for anxiety in BD. 2015 Thesis http://eprints.usm.my/40450/ http://eprints.usm.my/40450/1/Dr._Mohammad_Nabhan_Khalil_Azizan_%28Psychiatry%29-24_pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RC31-1245 Internal medicine
spellingShingle	RC31-1245 Internal medicine Khalil Azizan, Mohammad Nabhan The association of anxiety and mood symptoms in patients with bipolar disorders attending follow-up treatment
description	Background: Anxiety is common in Bipolar Disorders (BD). It is associated with poorer outcome in BD, for example increased in relapse rate and hospitalization, suicidality, substance abuse and more severe symptoms of mania and depression. Malaysian study regarding anxiety in BD is still lacking. Objective: The aim of this study was to determine prevalence of significant anxiety and its detection rate in psychiatric outpatient clinic. Sociodemographic and clinical characteristics associated with anxiety were also examined. Correlation between anxiety and mood symptoms and the burden of life events within one-year period were measured. Method: This is a cross-sectional study done in psychiatric outpatient clinic in Hospital Universiti Sains Malaysia. Sociodemographic and clinical data were acquired from selected samples and four self-rated scales [Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), Young Mania Rating Scale (YMRS) and Social Readjustment Rating Scale (SRRS)] were administered to measure mood symptoms, anxiety symptoms and the burden of life events within the previous one year. Regression and correlation analysis were done to examine relationship between anxiety symptoms and mood symptoms and sociodemographic and clinical data. Results: 20.5% of the total 132 participants had significant level of anxiety. Among these, only 29.3% were detected by clinicians. Anxiety level (BAI) in BD was positively and independently associated with Bipolar II Disorder, number of relapse and BDI score. There was strong positive correlation between BAI and BDI (r = 0.690, p <0.001). There was weak positive correlation between BAI and SRRS (r = 0.194, p =0.026). Conclusion: Anxiety in BD is poorly detected by clinicians and was associated with Bipolar II Disorder, higher frequency of relapse, more severe depression, and more burdens of life event within one-year period. Clinicians need to be sensitive in detecting anxiety in BD. More research is needed in finding effective treatment for anxiety in BD.
format	Thesis
qualification_level	Master's degree
author	Khalil Azizan, Mohammad Nabhan
author_facet	Khalil Azizan, Mohammad Nabhan
author_sort	Khalil Azizan, Mohammad Nabhan
title	The association of anxiety and mood symptoms in patients with bipolar disorders attending follow-up treatment
title_short	The association of anxiety and mood symptoms in patients with bipolar disorders attending follow-up treatment
title_full	The association of anxiety and mood symptoms in patients with bipolar disorders attending follow-up treatment
title_fullStr	The association of anxiety and mood symptoms in patients with bipolar disorders attending follow-up treatment
title_full_unstemmed	The association of anxiety and mood symptoms in patients with bipolar disorders attending follow-up treatment
title_sort	association of anxiety and mood symptoms in patients with bipolar disorders attending follow-up treatment
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2015
url	http://eprints.usm.my/40450/1/Dr._Mohammad_Nabhan_Khalil_Azizan_%28Psychiatry%29-24_pages.pdf
_version_	1747820793949061120

The association of anxiety and mood symptoms in patients with bipolar disorders attending follow-up treatment

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