Quality Of Stored Cord Blood In National Blood Centre Based On Maternal And Neonatal Factors

Latar Belakang: Darah tali pusat (UCB) merupakan sumber alternatif kepada sel tunjang alogenik hematopoetik bagi tujuan pemindahan. Kualiti darah tali pusat yang dikumpulkan bergantung pada kandungan hematopoetiknya yang secara langsung mempengaruhi hasil ‘engraftment’ dan terapeutik. Demi memast...

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Main Author:	Azmi, Nor Azhani
Format:	Thesis
Language:	English
Published:	2017
Subjects:	RK1-715 Dentistry
Online Access:	http://eprints.usm.my/40605/1/NOR_AZHANI_BINTI_AZMI.pdf
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id	my-usm-ep.40605
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spelling	my-usm-ep.406052019-04-12T05:25:05Z Quality Of Stored Cord Blood In National Blood Centre Based On Maternal And Neonatal Factors 2017 Azmi, Nor Azhani RK1-715 Dentistry Latar Belakang: Darah tali pusat (UCB) merupakan sumber alternatif kepada sel tunjang alogenik hematopoetik bagi tujuan pemindahan. Kualiti darah tali pusat yang dikumpulkan bergantung pada kandungan hematopoetiknya yang secara langsung mempengaruhi hasil ‘engraftment’ dan terapeutik. Demi memastikan kualiti darah tali pusat yang dikumpulkan terjamin, kriteria penerimaan darah tali pusat telah diwujudkan di bank tali pusat, Pusat Darah Negara (PDN) yang bersandarkan piawaian antarabangsa. Namun ia telah menyebabkan kadar penyingkiran unit darah tali pusat yang dikumpulkan agak tinggi. Kajian ini bertujuan untuk mengenalpasti hubungkait antara faktor penderma iaitu ibu dan bayi yang boleh mempengaruhi kualiti kandungan hematopoetik darah tali pusat untuk membantu dalam pemilihan penderma dan seterusnya mengurangkan pembaziran. Background: Umbilical cord blood (UCB) is an alternative source of allogeneic haematopoietic stem cells for transplantation. The quality of collected UCB depends on its haematopoietic content which directly influences the engraftment and the therapeutic outcome. To ensure the quality of stored UCB, the acceptance criteria were created at the UCB bank in National Blood Centre (NBC) based on established international standard, which resulted in a high discard rate. This study aims to determine the association of maternal and neonatal factors that could influence the quality of haematopoietic contents of the UCB collections thus guide the choice of donors and reduce wastage. 2017 Thesis http://eprints.usm.my/40605/ http://eprints.usm.my/40605/1/NOR_AZHANI_BINTI_AZMI.pdf application/pdf en public masters Universiti Sains Malaysia Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute)
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RK1-715 Dentistry
spellingShingle	RK1-715 Dentistry Azmi, Nor Azhani Quality Of Stored Cord Blood In National Blood Centre Based On Maternal And Neonatal Factors
description	Latar Belakang: Darah tali pusat (UCB) merupakan sumber alternatif kepada sel tunjang alogenik hematopoetik bagi tujuan pemindahan. Kualiti darah tali pusat yang dikumpulkan bergantung pada kandungan hematopoetiknya yang secara langsung mempengaruhi hasil ‘engraftment’ dan terapeutik. Demi memastikan kualiti darah tali pusat yang dikumpulkan terjamin, kriteria penerimaan darah tali pusat telah diwujudkan di bank tali pusat, Pusat Darah Negara (PDN) yang bersandarkan piawaian antarabangsa. Namun ia telah menyebabkan kadar penyingkiran unit darah tali pusat yang dikumpulkan agak tinggi. Kajian ini bertujuan untuk mengenalpasti hubungkait antara faktor penderma iaitu ibu dan bayi yang boleh mempengaruhi kualiti kandungan hematopoetik darah tali pusat untuk membantu dalam pemilihan penderma dan seterusnya mengurangkan pembaziran. Background: Umbilical cord blood (UCB) is an alternative source of allogeneic haematopoietic stem cells for transplantation. The quality of collected UCB depends on its haematopoietic content which directly influences the engraftment and the therapeutic outcome. To ensure the quality of stored UCB, the acceptance criteria were created at the UCB bank in National Blood Centre (NBC) based on established international standard, which resulted in a high discard rate. This study aims to determine the association of maternal and neonatal factors that could influence the quality of haematopoietic contents of the UCB collections thus guide the choice of donors and reduce wastage.
format	Thesis
qualification_level	Master's degree
author	Azmi, Nor Azhani
author_facet	Azmi, Nor Azhani
author_sort	Azmi, Nor Azhani
title	Quality Of Stored Cord Blood In National Blood Centre Based On Maternal And Neonatal Factors
title_short	Quality Of Stored Cord Blood In National Blood Centre Based On Maternal And Neonatal Factors
title_full	Quality Of Stored Cord Blood In National Blood Centre Based On Maternal And Neonatal Factors
title_fullStr	Quality Of Stored Cord Blood In National Blood Centre Based On Maternal And Neonatal Factors
title_full_unstemmed	Quality Of Stored Cord Blood In National Blood Centre Based On Maternal And Neonatal Factors
title_sort	quality of stored cord blood in national blood centre based on maternal and neonatal factors
granting_institution	Universiti Sains Malaysia
granting_department	Institut Perubatan & Pergigian Termaju (Advanced Medical & Dental Institute)
publishDate	2017
url	http://eprints.usm.my/40605/1/NOR_AZHANI_BINTI_AZMI.pdf
_version_	1747820797132537856

Quality Of Stored Cord Blood In National Blood Centre Based On Maternal And Neonatal Factors

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