In Vitro Selection of Rna Aptamers that Specifically Bind to 50kda Outer Membrane Protein of Salmonella Enterica Serovar Typhi

Demam kepialu merupakan penyakit bawaan makanan yang disebabkan oleh jangkitan bakteria Salmonella enterica serovar Typhi (S. Typhi). Demam kepialu masih lagi menjadi satu permasalahan kesihatan awam di kebanyakan negara mundur dan negara yang sedang membangun termasuk Malaysia. Dianggarkan kira-...

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Main Author: Ramli, Siti Mariam Mawarni
Format: Thesis
Language:English
Published: 2016
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Online Access:http://eprints.usm.my/40838/1/Dr.__Siti_Mariam_Mawarni_Ramli_TSTZ.pdf
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spelling my-usm-ep.408382018-06-28T06:19:08Z In Vitro Selection of Rna Aptamers that Specifically Bind to 50kda Outer Membrane Protein of Salmonella Enterica Serovar Typhi 2016-02 Ramli, Siti Mariam Mawarni R735-854 Medical education. Medical schools. Research Demam kepialu merupakan penyakit bawaan makanan yang disebabkan oleh jangkitan bakteria Salmonella enterica serovar Typhi (S. Typhi). Demam kepialu masih lagi menjadi satu permasalahan kesihatan awam di kebanyakan negara mundur dan negara yang sedang membangun termasuk Malaysia. Dianggarkan kira-kira 22 juta kes dan 216,000 kematian akibat daripada jangkitan S. Typhi telah dilaporkan di seluruh dunia setiap tahun. Membran protin luar (OMP) spesifik dengan berat molekul pada 50 ribu Dalton (50 kDa), daripada S. Typhi telah dilaporkan berkemungkinan memainkan peranan dalam jangkitan demam kepialu Typhoid fever is a food borne illness caused by the bacteria, Salmonella enterica serovar Typhi (S. Typhi). Typhoid fever remains a public health problem in many of the underdeveloped and developing countries including Malaysia. It has been estimated around 22 million cases and 216,000 related deaths occurred worldwide annually. The 50 kDa outer membrane protein (OMP) of S. Typhi has been considered as a possible candidate that plays role during the infection of typhoid. Therefore 50kDa OMP of S. Typhi was used as target molecule in detecting of S. Typhi. Currently, monoclonal and polyclonal antibodies were widely used in diagnostic kit development for antigen detection from the organisms that caused the disease 2016-02 Thesis http://eprints.usm.my/40838/ http://eprints.usm.my/40838/1/Dr.__Siti_Mariam_Mawarni_Ramli_TSTZ.pdf application/pdf en public masters USM Institut Penyelidikan Perubatan Molekul (Institute for Research in Molecular Medicine INFORMM
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R735-854 Medical education
Medical schools
Research
spellingShingle R735-854 Medical education
Medical schools
Research
Ramli, Siti Mariam Mawarni
In Vitro Selection of Rna Aptamers that Specifically Bind to 50kda Outer Membrane Protein of Salmonella Enterica Serovar Typhi
description Demam kepialu merupakan penyakit bawaan makanan yang disebabkan oleh jangkitan bakteria Salmonella enterica serovar Typhi (S. Typhi). Demam kepialu masih lagi menjadi satu permasalahan kesihatan awam di kebanyakan negara mundur dan negara yang sedang membangun termasuk Malaysia. Dianggarkan kira-kira 22 juta kes dan 216,000 kematian akibat daripada jangkitan S. Typhi telah dilaporkan di seluruh dunia setiap tahun. Membran protin luar (OMP) spesifik dengan berat molekul pada 50 ribu Dalton (50 kDa), daripada S. Typhi telah dilaporkan berkemungkinan memainkan peranan dalam jangkitan demam kepialu Typhoid fever is a food borne illness caused by the bacteria, Salmonella enterica serovar Typhi (S. Typhi). Typhoid fever remains a public health problem in many of the underdeveloped and developing countries including Malaysia. It has been estimated around 22 million cases and 216,000 related deaths occurred worldwide annually. The 50 kDa outer membrane protein (OMP) of S. Typhi has been considered as a possible candidate that plays role during the infection of typhoid. Therefore 50kDa OMP of S. Typhi was used as target molecule in detecting of S. Typhi. Currently, monoclonal and polyclonal antibodies were widely used in diagnostic kit development for antigen detection from the organisms that caused the disease
format Thesis
qualification_level Master's degree
author Ramli, Siti Mariam Mawarni
author_facet Ramli, Siti Mariam Mawarni
author_sort Ramli, Siti Mariam Mawarni
title In Vitro Selection of Rna Aptamers that Specifically Bind to 50kda Outer Membrane Protein of Salmonella Enterica Serovar Typhi
title_short In Vitro Selection of Rna Aptamers that Specifically Bind to 50kda Outer Membrane Protein of Salmonella Enterica Serovar Typhi
title_full In Vitro Selection of Rna Aptamers that Specifically Bind to 50kda Outer Membrane Protein of Salmonella Enterica Serovar Typhi
title_fullStr In Vitro Selection of Rna Aptamers that Specifically Bind to 50kda Outer Membrane Protein of Salmonella Enterica Serovar Typhi
title_full_unstemmed In Vitro Selection of Rna Aptamers that Specifically Bind to 50kda Outer Membrane Protein of Salmonella Enterica Serovar Typhi
title_sort in vitro selection of rna aptamers that specifically bind to 50kda outer membrane protein of salmonella enterica serovar typhi
granting_institution USM
granting_department Institut Penyelidikan Perubatan Molekul (Institute for Research in Molecular Medicine INFORMM
publishDate 2016
url http://eprints.usm.my/40838/1/Dr.__Siti_Mariam_Mawarni_Ramli_TSTZ.pdf
_version_ 1747820830996299776