Studies Of Antimicrobial Agent (Aa) Filled With Polypropylene (Pp) For Antimicrobial Application

Microbial infection is well recognized as a global threat to human health in biomedical field. Infections caused by microbes in hospitals are associated with usage of medical equipment and devices especially catheter. In this study, polymer matrix composite materials was produced by incorporated CuO...

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Main Author: Faudzi, Ku Nur ‘Izzati Ku Mohamad Faudzi
Format: Thesis
Language:English
Published: 2013
Subjects:
Online Access:http://eprints.usm.my/41217/1/KU_NUR_%E2%80%98IZZATI_BINTI_KU_MOHAMAD_FAUDZI.pdf
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spelling my-usm-ep.412172018-07-31T08:39:28Z Studies Of Antimicrobial Agent (Aa) Filled With Polypropylene (Pp) For Antimicrobial Application 2013 Faudzi, Ku Nur ‘Izzati Ku Mohamad Faudzi TA404 Composite materials Microbial infection is well recognized as a global threat to human health in biomedical field. Infections caused by microbes in hospitals are associated with usage of medical equipment and devices especially catheter. In this study, polymer matrix composite materials was produced by incorporated CuO and TiO2 particles into polypropylene through mixing process in Haake internal mixer at 185°C for 10 minutes followed by compression moulding process. Parameters used included variety composition of PP, CuO, TiO2, Ag, AgNO3 and ZnO and temperature of cooling process at QCW (10°C), QWW (30°C), CP and SC. Characterizations used included optical microscope, SEM, XRD, DSC and antimicrobial testing (embedded method and colony count). There were three stages involved like effect of using different types of AA embedded in PP matrix, effect of mixture of two to three different types of AA and colouring agent embedded in PP matrix and effect of different cooling conditions. At stage 1, CuO/PP and TiO2/PP shows good distributions particles and good antimicrobial testing which were then used in next stage. PP/CuO/TiO2/C had been selected as the best sample because of well distribution AA in PP matrix, low crystallinity and good antimicrobial resistance. Quenching method in warm water made PP/CuO/TiO2/C sample more amorphous and increase antimicrobial efficacy. Conclusively,PP/CuO/TiO2/C has high potential to reduce infection caused by microbes. It also can be used as new replacement to current catheter in biomedical application 2013 Thesis http://eprints.usm.my/41217/ http://eprints.usm.my/41217/1/KU_NUR_%E2%80%98IZZATI_BINTI_KU_MOHAMAD_FAUDZI.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Kejuruteraan Bahan dan Sumber Mineral
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic TA404 Composite materials
spellingShingle TA404 Composite materials
Faudzi, Ku Nur ‘Izzati Ku Mohamad Faudzi
Studies Of Antimicrobial Agent (Aa) Filled With Polypropylene (Pp) For Antimicrobial Application
description Microbial infection is well recognized as a global threat to human health in biomedical field. Infections caused by microbes in hospitals are associated with usage of medical equipment and devices especially catheter. In this study, polymer matrix composite materials was produced by incorporated CuO and TiO2 particles into polypropylene through mixing process in Haake internal mixer at 185°C for 10 minutes followed by compression moulding process. Parameters used included variety composition of PP, CuO, TiO2, Ag, AgNO3 and ZnO and temperature of cooling process at QCW (10°C), QWW (30°C), CP and SC. Characterizations used included optical microscope, SEM, XRD, DSC and antimicrobial testing (embedded method and colony count). There were three stages involved like effect of using different types of AA embedded in PP matrix, effect of mixture of two to three different types of AA and colouring agent embedded in PP matrix and effect of different cooling conditions. At stage 1, CuO/PP and TiO2/PP shows good distributions particles and good antimicrobial testing which were then used in next stage. PP/CuO/TiO2/C had been selected as the best sample because of well distribution AA in PP matrix, low crystallinity and good antimicrobial resistance. Quenching method in warm water made PP/CuO/TiO2/C sample more amorphous and increase antimicrobial efficacy. Conclusively,PP/CuO/TiO2/C has high potential to reduce infection caused by microbes. It also can be used as new replacement to current catheter in biomedical application
format Thesis
qualification_level Master's degree
author Faudzi, Ku Nur ‘Izzati Ku Mohamad Faudzi
author_facet Faudzi, Ku Nur ‘Izzati Ku Mohamad Faudzi
author_sort Faudzi, Ku Nur ‘Izzati Ku Mohamad Faudzi
title Studies Of Antimicrobial Agent (Aa) Filled With Polypropylene (Pp) For Antimicrobial Application
title_short Studies Of Antimicrobial Agent (Aa) Filled With Polypropylene (Pp) For Antimicrobial Application
title_full Studies Of Antimicrobial Agent (Aa) Filled With Polypropylene (Pp) For Antimicrobial Application
title_fullStr Studies Of Antimicrobial Agent (Aa) Filled With Polypropylene (Pp) For Antimicrobial Application
title_full_unstemmed Studies Of Antimicrobial Agent (Aa) Filled With Polypropylene (Pp) For Antimicrobial Application
title_sort studies of antimicrobial agent (aa) filled with polypropylene (pp) for antimicrobial application
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Kejuruteraan Bahan dan Sumber Mineral
publishDate 2013
url http://eprints.usm.my/41217/1/KU_NUR_%E2%80%98IZZATI_BINTI_KU_MOHAMAD_FAUDZI.pdf
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