In Vitro Antioxidant, Antiangiogenic And Vasorelaxant Studies Of Clerodendron Serratum (Spreng.) Leaves Extracts

In Vitro Antioxidant, Antiangiogenic And Vasorelaxant Studies Of Clerodendron Serratum (Spreng.) Leaves Extracts

Clerodendron serratum (Spreng.) leaves from Verbenacea family, locally known as “Timba Tasek” is a traditional Malay medicinal plant used for treating various diseases. However, the present works were focused on evaluating its antiangiogenic, vasorelaxant and antioxidant activities as well as chemic...

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Main Author: Mohamed, Ali Jimale
Format: Thesis
Language:English
Published: 2011
Subjects:
RS1-441 Pharmacy and materia medica
Online Access:http://eprints.usm.my/41367/1/ALI_JIMALE_MOHAMED.pdf
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spelling my-usm-ep.413672019-04-12T05:26:33Z In Vitro Antioxidant, Antiangiogenic And Vasorelaxant Studies Of Clerodendron Serratum (Spreng.) Leaves Extracts 2011-06 Mohamed, Ali Jimale RS1-441 Pharmacy and materia medica Clerodendron serratum (Spreng.) leaves from Verbenacea family, locally known as “Timba Tasek” is a traditional Malay medicinal plant used for treating various diseases. However, the present works were focused on evaluating its antiangiogenic, vasorelaxant and antioxidant activities as well as chemical profiles of the leaves extracts. The dried powdered leaves of C. serratum were serially macerated with petroleum ether (a defatting step), chloroform, methanol and water. The antiangiogenic activity (the inhibitory effects of these extracts on blood vessel growth/formation) was studied using rat aortic ring assay. The vasorelaxant activity was studied by examining the inhibitory effect of C. serratum extract on contractile responses of cumulative doses of noradrenaline in isolated rat aortic ring preparation. 2011-06 Thesis http://eprints.usm.my/41367/ http://eprints.usm.my/41367/1/ALI_JIMALE_MOHAMED.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic RS1-441 Pharmacy and materia medica
spellingShingle RS1-441 Pharmacy and materia medica
Mohamed, Ali Jimale
In Vitro Antioxidant, Antiangiogenic And Vasorelaxant Studies Of Clerodendron Serratum (Spreng.) Leaves Extracts
description Clerodendron serratum (Spreng.) leaves from Verbenacea family, locally known as “Timba Tasek” is a traditional Malay medicinal plant used for treating various diseases. However, the present works were focused on evaluating its antiangiogenic, vasorelaxant and antioxidant activities as well as chemical profiles of the leaves extracts. The dried powdered leaves of C. serratum were serially macerated with petroleum ether (a defatting step), chloroform, methanol and water. The antiangiogenic activity (the inhibitory effects of these extracts on blood vessel growth/formation) was studied using rat aortic ring assay. The vasorelaxant activity was studied by examining the inhibitory effect of C. serratum extract on contractile responses of cumulative doses of noradrenaline in isolated rat aortic ring preparation.
format Thesis
qualification_level Master's degree
author Mohamed, Ali Jimale
author_facet Mohamed, Ali Jimale
author_sort Mohamed, Ali Jimale
title In Vitro Antioxidant, Antiangiogenic And Vasorelaxant Studies Of Clerodendron Serratum (Spreng.) Leaves Extracts
title_short In Vitro Antioxidant, Antiangiogenic And Vasorelaxant Studies Of Clerodendron Serratum (Spreng.) Leaves Extracts
title_full In Vitro Antioxidant, Antiangiogenic And Vasorelaxant Studies Of Clerodendron Serratum (Spreng.) Leaves Extracts
title_fullStr In Vitro Antioxidant, Antiangiogenic And Vasorelaxant Studies Of Clerodendron Serratum (Spreng.) Leaves Extracts
title_full_unstemmed In Vitro Antioxidant, Antiangiogenic And Vasorelaxant Studies Of Clerodendron Serratum (Spreng.) Leaves Extracts
title_sort in vitro antioxidant, antiangiogenic and vasorelaxant studies of clerodendron serratum (spreng.) leaves extracts
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Farmasi
publishDate 2011
url http://eprints.usm.my/41367/1/ALI_JIMALE_MOHAMED.pdf
_version_ 1747820918918348800

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