A pilot study of sterile saline versus reverse osmosis water in traumatic laceration wound cleansing in Emergency Department in Hospital Universiti Sains Malaysia, Kelantan and Hospital Tengku Ampuan Afzan, Pahang

Introduction: Traumatic laceration wound is a common reason for people seeking treatment in emergency care setting. As for current practice, sterile saline is still the most common agent used in cleansing or irrigating the wound in the emergency department. In overseas, there have been studies on...

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Main Author:	Hashim, Anas Amri
Format:	Thesis
Language:	English
Published:	2015
Subjects:	RD Surgery
Online Access:	http://eprints.usm.my/41516/1/Dr._Anas_Amri_Hashim-OCR.pdf
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id	my-usm-ep.41516
record_format	uketd_dc
spelling	my-usm-ep.415162019-04-12T05:25:33Z A pilot study of sterile saline versus reverse osmosis water in traumatic laceration wound cleansing in Emergency Department in Hospital Universiti Sains Malaysia, Kelantan and Hospital Tengku Ampuan Afzan, Pahang 2015-12 Hashim, Anas Amri RD Surgery Introduction: Traumatic laceration wound is a common reason for people seeking treatment in emergency care setting. As for current practice, sterile saline is still the most common agent used in cleansing or irrigating the wound in the emergency department. In overseas, there have been studies on alternative cleansing agent particularly tap water, which have showed equal or better outcomes in term of wound infection. There is no previous study been conducted on wound cleansing using Reverse Osmosis water. Objectives: To compare the rate of wound infection between sterile saline and reverse osmosis water cleansing for traumatic laceration wound. Method: This study was a multicenter, prospective, randomised controlled trial conducted at two tertiary hospitals. Subjects were a convenience sample of adults presenting with acute simple traumatic laceration requiring wound cleansing. They were randomized using block randomization method to irrigation with ‘sterile saline’ or ‘reverse osmosis’ water. Wounds were closed in the standard fashion. Follow-ups were done on day 5 and 14 after the intervention to assess for outcome or wound infection Results: A total of 48 patients (n=48) were selected and randomised into RO water group (n=24) and Saline group (n=20) (4 patients withdrew). The infection rate for sterile saline cleansing was 5% (95% CI -4.55%, 14.55%) compared to RO cleansing which was 4.17% (95% CI -3.83%, 12.17%). Relative risk for RO water group was 0.834 (95%CI 0.056, 12.494) compare to saline group. Fisher’s Exact test showed no significant effect on type of cleansing agent on wound infection. Conclusion: There was no significant difference between reverse osmosis and saline on wound infection. Reverse osmosis water can be considered as alternative cleansing agent to sterile saline in acute uncomplicated traumatic laceration wounds. 2015-12 Thesis http://eprints.usm.my/41516/ http://eprints.usm.my/41516/1/Dr._Anas_Amri_Hashim-OCR.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RD Surgery
spellingShingle	RD Surgery Hashim, Anas Amri A pilot study of sterile saline versus reverse osmosis water in traumatic laceration wound cleansing in Emergency Department in Hospital Universiti Sains Malaysia, Kelantan and Hospital Tengku Ampuan Afzan, Pahang
description	Introduction: Traumatic laceration wound is a common reason for people seeking treatment in emergency care setting. As for current practice, sterile saline is still the most common agent used in cleansing or irrigating the wound in the emergency department. In overseas, there have been studies on alternative cleansing agent particularly tap water, which have showed equal or better outcomes in term of wound infection. There is no previous study been conducted on wound cleansing using Reverse Osmosis water. Objectives: To compare the rate of wound infection between sterile saline and reverse osmosis water cleansing for traumatic laceration wound. Method: This study was a multicenter, prospective, randomised controlled trial conducted at two tertiary hospitals. Subjects were a convenience sample of adults presenting with acute simple traumatic laceration requiring wound cleansing. They were randomized using block randomization method to irrigation with ‘sterile saline’ or ‘reverse osmosis’ water. Wounds were closed in the standard fashion. Follow-ups were done on day 5 and 14 after the intervention to assess for outcome or wound infection Results: A total of 48 patients (n=48) were selected and randomised into RO water group (n=24) and Saline group (n=20) (4 patients withdrew). The infection rate for sterile saline cleansing was 5% (95% CI -4.55%, 14.55%) compared to RO cleansing which was 4.17% (95% CI -3.83%, 12.17%). Relative risk for RO water group was 0.834 (95%CI 0.056, 12.494) compare to saline group. Fisher’s Exact test showed no significant effect on type of cleansing agent on wound infection. Conclusion: There was no significant difference between reverse osmosis and saline on wound infection. Reverse osmosis water can be considered as alternative cleansing agent to sterile saline in acute uncomplicated traumatic laceration wounds.
format	Thesis
qualification_level	Master's degree
author	Hashim, Anas Amri
author_facet	Hashim, Anas Amri
author_sort	Hashim, Anas Amri
title	A pilot study of sterile saline versus reverse osmosis water in traumatic laceration wound cleansing in Emergency Department in Hospital Universiti Sains Malaysia, Kelantan and Hospital Tengku Ampuan Afzan, Pahang
title_short	A pilot study of sterile saline versus reverse osmosis water in traumatic laceration wound cleansing in Emergency Department in Hospital Universiti Sains Malaysia, Kelantan and Hospital Tengku Ampuan Afzan, Pahang
title_full	A pilot study of sterile saline versus reverse osmosis water in traumatic laceration wound cleansing in Emergency Department in Hospital Universiti Sains Malaysia, Kelantan and Hospital Tengku Ampuan Afzan, Pahang
title_fullStr	A pilot study of sterile saline versus reverse osmosis water in traumatic laceration wound cleansing in Emergency Department in Hospital Universiti Sains Malaysia, Kelantan and Hospital Tengku Ampuan Afzan, Pahang
title_full_unstemmed	A pilot study of sterile saline versus reverse osmosis water in traumatic laceration wound cleansing in Emergency Department in Hospital Universiti Sains Malaysia, Kelantan and Hospital Tengku Ampuan Afzan, Pahang
title_sort	pilot study of sterile saline versus reverse osmosis water in traumatic laceration wound cleansing in emergency department in hospital universiti sains malaysia, kelantan and hospital tengku ampuan afzan, pahang
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2015
url	http://eprints.usm.my/41516/1/Dr._Anas_Amri_Hashim-OCR.pdf
_version_	1747820925503406080

A pilot study of sterile saline versus reverse osmosis water in traumatic laceration wound cleansing in Emergency Department in Hospital Universiti Sains Malaysia, Kelantan and Hospital Tengku Ampuan Afzan, Pahang

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