Evaluation Of Combined Metformin-Lovastatin Therapy In The Treatment Of Diabetic Type 2 Patients With Dyslipidemia In Hospital Pulau Pinang
Diabetes type 2 is characterized by the presence of insulin resistance which frequently co-exists with multiple cardiovascular risk factors. Dyslipidemia is a well-recognized and modifiable risk factor that should be identified and treated aggressively to prevent the onset and prognosis of cardio...
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my-usm-ep.416892019-04-12T05:26:58Z Evaluation Of Combined Metformin-Lovastatin Therapy In The Treatment Of Diabetic Type 2 Patients With Dyslipidemia In Hospital Pulau Pinang 2010 Ghaith, Nada Faisal Zaki RS1-441 Pharmacy and materia medica Diabetes type 2 is characterized by the presence of insulin resistance which frequently co-exists with multiple cardiovascular risk factors. Dyslipidemia is a well-recognized and modifiable risk factor that should be identified and treated aggressively to prevent the onset and prognosis of cardiovascular disease. This study aimed to assess the clinical outcomes behind the usage of metformin and lovastatin in the treatment of diabetes type 2 patients with dyslipidemia. Furthermore, an evaluation of difference in therapeutic response was done according to race and gender. A retrospective observational study was performed at the outpatient clinic of Hospital Pulau Pinang, Malaysia. Demographic, medication profile, and laboratory tests information were collected. Data were analyzed by using Statistical Package of Social Sciences (SPSS) program version 15. From 873 medical records, only 501 patients met the inclusion criteria of this study. Females constituted 55.9%, while 44.1% were males. Racial distribution showed that Chinese were 41.7%, Malay 34.3% and Indians 24%. Significantly, Chinese showed the highest percentage (97.5%) of controlled HDL levels. Unlike males, females demonstrated the highest mean TC and HDL values (5.40 ± 1.09 mmol/l and 1.32 ± 0.29 mmol/l respectively) significantly. 2010 Thesis http://eprints.usm.my/41689/ http://eprints.usm.my/41689/1/Nada_Faisal_HJ.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Farmasi |
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USM Institutional Repository |
| language |
English |
| topic |
RS1-441 Pharmacy and materia medica |
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RS1-441 Pharmacy and materia medica Ghaith, Nada Faisal Zaki Evaluation Of Combined Metformin-Lovastatin Therapy In The Treatment Of Diabetic Type 2 Patients With Dyslipidemia In Hospital Pulau Pinang |
| description |
Diabetes type 2 is characterized by the presence of insulin resistance which
frequently co-exists with multiple cardiovascular risk factors. Dyslipidemia
is a well-recognized and modifiable risk factor that should be identified and
treated aggressively to prevent the onset and prognosis of cardiovascular
disease. This study aimed to assess the clinical outcomes behind the usage
of metformin and lovastatin in the treatment of diabetes type 2 patients with
dyslipidemia. Furthermore, an evaluation of difference in therapeutic
response was done according to race and gender. A retrospective
observational study was performed at the outpatient clinic of Hospital Pulau
Pinang, Malaysia. Demographic, medication profile, and laboratory tests
information were collected. Data were analyzed by using Statistical Package
of Social Sciences (SPSS) program version 15. From 873 medical records,
only 501 patients met the inclusion criteria of this study. Females constituted
55.9%, while 44.1% were males. Racial distribution showed that Chinese
were 41.7%, Malay 34.3% and Indians 24%. Significantly, Chinese showed
the highest percentage (97.5%) of controlled HDL levels. Unlike males,
females demonstrated the highest mean TC and HDL values (5.40 ± 1.09
mmol/l and 1.32 ± 0.29 mmol/l respectively) significantly. |
| format |
Thesis |
| qualification_level |
Master's degree |
| author |
Ghaith, Nada Faisal Zaki |
| author_facet |
Ghaith, Nada Faisal Zaki |
| author_sort |
Ghaith, Nada Faisal Zaki |
| title |
Evaluation Of Combined Metformin-Lovastatin Therapy In The Treatment Of Diabetic Type 2 Patients With Dyslipidemia In Hospital Pulau Pinang |
| title_short |
Evaluation Of Combined Metformin-Lovastatin Therapy In The Treatment Of Diabetic Type 2 Patients With Dyslipidemia In Hospital Pulau Pinang |
| title_full |
Evaluation Of Combined Metformin-Lovastatin Therapy In The Treatment Of Diabetic Type 2 Patients With Dyslipidemia In Hospital Pulau Pinang |
| title_fullStr |
Evaluation Of Combined Metformin-Lovastatin Therapy In The Treatment Of Diabetic Type 2 Patients With Dyslipidemia In Hospital Pulau Pinang |
| title_full_unstemmed |
Evaluation Of Combined Metformin-Lovastatin Therapy In The Treatment Of Diabetic Type 2 Patients With Dyslipidemia In Hospital Pulau Pinang |
| title_sort |
evaluation of combined metformin-lovastatin therapy in the treatment of diabetic type 2 patients with dyslipidemia in hospital pulau pinang |
| granting_institution |
Universiti Sains Malaysia |
| granting_department |
Pusat Pengajian Sains Farmasi |
| publishDate |
2010 |
| url |
http://eprints.usm.my/41689/1/Nada_Faisal_HJ.pdf |
| _version_ |
1747820956841148416 |