Syntheses And Antibacterial Screening Of Juglone Derivatives

The juglone natural product has been used as the starting material in the syntheses of various bioactive quinones like ochromycinone. The present study involves the syntheses of juglone derivatives from both juglone and non-juglone starting materials. The ochromycinone precursor, 1,2,3,4-tetrahydro-...

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Main Author:	Tan , Daniel Teoh Chuan
Format:	Thesis
Language:	English
Published:	2010
Subjects:	QD1-65 General Including alchemy
Online Access:	http://eprints.usm.my/41745/1/DANIAL_TAN_TEOH_CHUAN.pdf
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id	my-usm-ep.41745
record_format	uketd_dc
spelling	my-usm-ep.417452019-04-12T05:26:46Z Syntheses And Antibacterial Screening Of Juglone Derivatives 2010-11 Tan , Daniel Teoh Chuan QD1-65 General Including alchemy The juglone natural product has been used as the starting material in the syntheses of various bioactive quinones like ochromycinone. The present study involves the syntheses of juglone derivatives from both juglone and non-juglone starting materials. The ochromycinone precursor, 1,2,3,4-tetrahydro-8-hydroxy-3-methylbenz[a] anthracene-7,12-dione (19) was synthesised from juglone in two steps. The first step was the Diels-Alder reaction and the second step was the aromatisation reaction. In addition, a new para-nitrojuglone derivative (51) was obtained as the sole isomeric product from the direct nitration of juglone. 2010-11 Thesis http://eprints.usm.my/41745/ http://eprints.usm.my/41745/1/DANIAL_TAN_TEOH_CHUAN.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Kimia
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	QD1-65 General Including alchemy
spellingShingle	QD1-65 General Including alchemy Tan , Daniel Teoh Chuan Syntheses And Antibacterial Screening Of Juglone Derivatives
description	The juglone natural product has been used as the starting material in the syntheses of various bioactive quinones like ochromycinone. The present study involves the syntheses of juglone derivatives from both juglone and non-juglone starting materials. The ochromycinone precursor, 1,2,3,4-tetrahydro-8-hydroxy-3-methylbenz[a] anthracene-7,12-dione (19) was synthesised from juglone in two steps. The first step was the Diels-Alder reaction and the second step was the aromatisation reaction. In addition, a new para-nitrojuglone derivative (51) was obtained as the sole isomeric product from the direct nitration of juglone.
format	Thesis
qualification_level	Master's degree
author	Tan , Daniel Teoh Chuan
author_facet	Tan , Daniel Teoh Chuan
author_sort	Tan , Daniel Teoh Chuan
title	Syntheses And Antibacterial Screening Of Juglone Derivatives
title_short	Syntheses And Antibacterial Screening Of Juglone Derivatives
title_full	Syntheses And Antibacterial Screening Of Juglone Derivatives
title_fullStr	Syntheses And Antibacterial Screening Of Juglone Derivatives
title_full_unstemmed	Syntheses And Antibacterial Screening Of Juglone Derivatives
title_sort	syntheses and antibacterial screening of juglone derivatives
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Kimia
publishDate	2010
url	http://eprints.usm.my/41745/1/DANIAL_TAN_TEOH_CHUAN.pdf
_version_	1747820964938252288

Syntheses And Antibacterial Screening Of Juglone Derivatives

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