Anticancer Effects Of Tualang Honey On 7,12-Dimethylbenz(A)Anthracene (DMBA)-Induced Mammary Carcinoma In Rats

Tualang honey (TH) has been reported to have antiproliferative effect and induces apoptosis in various cancer cell lines. The present study was conducted to evaluate the effects of TH on the initiation and progression of 7,12- dimethylbenz(α)anthracene (DMBA)-induced mammary carcinoma in rats. A pr...

Full description

Saved in:
Bibliographic Details
Main Author: Kadir, Erazuliana Abd
Format: Thesis
Language:English
Published: 2011
Subjects:
Online Access:http://eprints.usm.my/41783/1/ERAZULIANA_ABD_KADIR.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-usm-ep.41783
record_format uketd_dc
spelling my-usm-ep.417832019-04-12T05:26:43Z Anticancer Effects Of Tualang Honey On 7,12-Dimethylbenz(A)Anthracene (DMBA)-Induced Mammary Carcinoma In Rats 2011 Kadir, Erazuliana Abd R5-920 Medicine (General) Tualang honey (TH) has been reported to have antiproliferative effect and induces apoptosis in various cancer cell lines. The present study was conducted to evaluate the effects of TH on the initiation and progression of 7,12- dimethylbenz(α)anthracene (DMBA)-induced mammary carcinoma in rats. A preliminary study was conducted to establish the optimum DMBA dose for cancer induction. Single administration of 20 or 25 mg DMBA to 45 to 48 days old female rats with bodyweight of less or more than 120 g respectively was able to induce 50% carcinoma incidence. 2011 Thesis http://eprints.usm.my/41783/ http://eprints.usm.my/41783/1/ERAZULIANA_ABD_KADIR.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R5-920 Medicine (General)
spellingShingle R5-920 Medicine (General)
Kadir, Erazuliana Abd
Anticancer Effects Of Tualang Honey On 7,12-Dimethylbenz(A)Anthracene (DMBA)-Induced Mammary Carcinoma In Rats
description Tualang honey (TH) has been reported to have antiproliferative effect and induces apoptosis in various cancer cell lines. The present study was conducted to evaluate the effects of TH on the initiation and progression of 7,12- dimethylbenz(α)anthracene (DMBA)-induced mammary carcinoma in rats. A preliminary study was conducted to establish the optimum DMBA dose for cancer induction. Single administration of 20 or 25 mg DMBA to 45 to 48 days old female rats with bodyweight of less or more than 120 g respectively was able to induce 50% carcinoma incidence.
format Thesis
qualification_level Master's degree
author Kadir, Erazuliana Abd
author_facet Kadir, Erazuliana Abd
author_sort Kadir, Erazuliana Abd
title Anticancer Effects Of Tualang Honey On 7,12-Dimethylbenz(A)Anthracene (DMBA)-Induced Mammary Carcinoma In Rats
title_short Anticancer Effects Of Tualang Honey On 7,12-Dimethylbenz(A)Anthracene (DMBA)-Induced Mammary Carcinoma In Rats
title_full Anticancer Effects Of Tualang Honey On 7,12-Dimethylbenz(A)Anthracene (DMBA)-Induced Mammary Carcinoma In Rats
title_fullStr Anticancer Effects Of Tualang Honey On 7,12-Dimethylbenz(A)Anthracene (DMBA)-Induced Mammary Carcinoma In Rats
title_full_unstemmed Anticancer Effects Of Tualang Honey On 7,12-Dimethylbenz(A)Anthracene (DMBA)-Induced Mammary Carcinoma In Rats
title_sort anticancer effects of tualang honey on 7,12-dimethylbenz(a)anthracene (dmba)-induced mammary carcinoma in rats
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Perubatan
publishDate 2011
url http://eprints.usm.my/41783/1/ERAZULIANA_ABD_KADIR.pdf
_version_ 1747820969349611520