Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
Four different types of compounds were successfully synthesized and characterized. The syntheses of these compounds involved benzylation, addition elimination and cyclization reactions. The structures of the synthesized compounds were confirmed by melting points, FTIR, HRMS, 1D and 2D NMR spectrosco...
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my-usm-ep.420632019-04-12T05:26:59Z Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives 2010 al-Douh, Mohammed Hadi Saeed QD1-999 Chemistry Four different types of compounds were successfully synthesized and characterized. The syntheses of these compounds involved benzylation, addition elimination and cyclization reactions. The structures of the synthesized compounds were confirmed by melting points, FTIR, HRMS, 1D and 2D NMR spectroscopy and X–ray crystallography. The first type of these compounds is 2-benzyloxy-3- methoxybenzaldehyde 75, which was synthesized by the reaction of o-vanillin with benzyl bromide in acetone as the solvent and K2CO3 as a base in the presence of tetra-n-butylammonium iodide (TBAI) as catalyst. 2010 Thesis http://eprints.usm.my/42063/ http://eprints.usm.my/42063/1/MOHAMMED_HADI_SAEED_AL%E2%80%93DOUH.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Kimia |
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English |
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QD1-999 Chemistry |
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QD1-999 Chemistry al-Douh, Mohammed Hadi Saeed Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives |
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Four different types of compounds were successfully synthesized and characterized. The syntheses of these compounds involved benzylation, addition elimination and cyclization reactions. The structures of the synthesized compounds were confirmed by melting points, FTIR, HRMS, 1D and 2D NMR spectroscopy and X–ray crystallography. The first type of these compounds is 2-benzyloxy-3-
methoxybenzaldehyde 75, which was synthesized by the reaction of o-vanillin with benzyl bromide in acetone as the solvent and K2CO3 as a base in the presence of tetra-n-butylammonium iodide (TBAI) as catalyst. |
format |
Thesis |
qualification_name |
Doctor of Philosophy (PhD.) |
qualification_level |
Doctorate |
author |
al-Douh, Mohammed Hadi Saeed |
author_facet |
al-Douh, Mohammed Hadi Saeed |
author_sort |
al-Douh, Mohammed Hadi Saeed |
title |
Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
|
title_short |
Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
|
title_full |
Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
|
title_fullStr |
Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
|
title_full_unstemmed |
Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
|
title_sort |
synthesis, characterization and anti-proliferation study of some benzimidazole derivatives |
granting_institution |
Universiti Sains Malaysia |
granting_department |
Pusat Pengajian Sains Kimia |
publishDate |
2010 |
url |
http://eprints.usm.my/42063/1/MOHAMMED_HADI_SAEED_AL%E2%80%93DOUH.pdf |
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1747821019836448768 |