A Clinical And Pharmacogenetic Investigation Of Methadone Maintenance Therapy (MMT) In Opiate Dependent Individuals

Over time, many discoveries revolutionized medicine. Methadone has revolutionized the management of opiate dependence. With MMT, most patients respond well and their health improves. Its complex pharmacology and “opiophobia” however impede its full usefulness. Among the “opiophobics”, alternative th...

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Main Author: Mohamad, Nasir
Format: Thesis
Language:English
Published: 2011
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Online Access:http://eprints.usm.my/42134/1/NASIR_MOHAMAD.pdf
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spelling my-usm-ep.421342019-04-12T05:26:37Z A Clinical And Pharmacogenetic Investigation Of Methadone Maintenance Therapy (MMT) In Opiate Dependent Individuals 2011-05 Mohamad, Nasir R735-854 Medical education. Medical schools. Research Over time, many discoveries revolutionized medicine. Methadone has revolutionized the management of opiate dependence. With MMT, most patients respond well and their health improves. Its complex pharmacology and “opiophobia” however impede its full usefulness. Among the “opiophobics”, alternative therapies with, as an example, Chinese medicines, are frequently sought and advocated. We performed a laboratory and clinical study with the objective of investigating factors that predict successful MMT program, in an effort to improve therapy with methadone and to help us develop guidelines on the optimization of MMT. We also studied the effect of a Chinese herb, BioLitrin in patients maintained on MMT to evaluate its role as an adjunct to MMT. 2011-05 Thesis http://eprints.usm.my/42134/ http://eprints.usm.my/42134/1/NASIR_MOHAMAD.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Institut Penyelidikan Perubatan Molekul
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R735-854 Medical education
Medical schools
Research
spellingShingle R735-854 Medical education
Medical schools
Research
Mohamad, Nasir
A Clinical And Pharmacogenetic Investigation Of Methadone Maintenance Therapy (MMT) In Opiate Dependent Individuals
description Over time, many discoveries revolutionized medicine. Methadone has revolutionized the management of opiate dependence. With MMT, most patients respond well and their health improves. Its complex pharmacology and “opiophobia” however impede its full usefulness. Among the “opiophobics”, alternative therapies with, as an example, Chinese medicines, are frequently sought and advocated. We performed a laboratory and clinical study with the objective of investigating factors that predict successful MMT program, in an effort to improve therapy with methadone and to help us develop guidelines on the optimization of MMT. We also studied the effect of a Chinese herb, BioLitrin in patients maintained on MMT to evaluate its role as an adjunct to MMT.
format Thesis
qualification_name Doctor of Philosophy (PhD.)
qualification_level Doctorate
author Mohamad, Nasir
author_facet Mohamad, Nasir
author_sort Mohamad, Nasir
title A Clinical And Pharmacogenetic Investigation Of Methadone Maintenance Therapy (MMT) In Opiate Dependent Individuals
title_short A Clinical And Pharmacogenetic Investigation Of Methadone Maintenance Therapy (MMT) In Opiate Dependent Individuals
title_full A Clinical And Pharmacogenetic Investigation Of Methadone Maintenance Therapy (MMT) In Opiate Dependent Individuals
title_fullStr A Clinical And Pharmacogenetic Investigation Of Methadone Maintenance Therapy (MMT) In Opiate Dependent Individuals
title_full_unstemmed A Clinical And Pharmacogenetic Investigation Of Methadone Maintenance Therapy (MMT) In Opiate Dependent Individuals
title_sort clinical and pharmacogenetic investigation of methadone maintenance therapy (mmt) in opiate dependent individuals
granting_institution Universiti Sains Malaysia
granting_department Institut Penyelidikan Perubatan Molekul
publishDate 2011
url http://eprints.usm.my/42134/1/NASIR_MOHAMAD.pdf
_version_ 1747821030320111616