Antiproliferative Effects Of The Orthosiphon Stamineus And Tualang Honey On Oral Squamous Cell Carcinoma And Human Osteosarcoma Cell Lines

Cancer is the fourth leading cause of death in Malaysia with almost 30,000 people contracting the disease annually. One of the important research fields is the beneficial effects of plants and natural products as effective chemotherapeutic agents. Honey exhibits a broad spectrum of therapeutic pr...

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Main Author:	Al-Ghashm, Abdulmlik
Format:	Thesis
Language:	English
Published:	2010
Subjects:	R5-130.5 General works
Online Access:	http://eprints.usm.my/42466/1/Abdulmlik_Al-Ghashm_HJ.pdf
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id	my-usm-ep.42466
record_format	uketd_dc
spelling	my-usm-ep.424662019-04-12T05:26:46Z Antiproliferative Effects Of The Orthosiphon Stamineus And Tualang Honey On Oral Squamous Cell Carcinoma And Human Osteosarcoma Cell Lines 2010-11 Al-Ghashm, Abdulmlik R5-130.5 General works Cancer is the fourth leading cause of death in Malaysia with almost 30,000 people contracting the disease annually. One of the important research fields is the beneficial effects of plants and natural products as effective chemotherapeutic agents. Honey exhibits a broad spectrum of therapeutic properties including antibacterial, antifungal, anti-inflammatory and moderate anticancer effects. It contains many biologically active compounds such as caffeic acid, caffeic acid phenethyl ester and flavonoid glycones which have been proven to exhibit inhibitory effect on tumor cell proliferation. Orthosiphon stamineus (O. stamineus) or ‘misai kucing’ is a popular traditional folk medicine used as medicinal herb for many centuries. It has many medicinal properties such as antioxidant activity, antifungal activity, diuretic activity, antidiabetic activity, anti-inflammatory activity. No previous study has been done to evaluate the effect of Tualang honey and O. stamineus on oral squamous cell carcinoma (OSCC) and human osteosarcoma (HOS). This study was aimed to verify the antiproliferative activity for several concentrations of Tualang honey, O. stamineus and mixed concentrations of honey and O. stamineus on OSCC and HOS cell lines. Several doses of Tualang honey (1% - 20%), several concentrations of O. stamineus (100μg/ml to 1mg/ml) and several mixed solutions of both were applied on OSCC and HOS cell culture for 3, 6, 12, 24, 48 and 72 hours. 2010-11 Thesis http://eprints.usm.my/42466/ http://eprints.usm.my/42466/1/Abdulmlik_Al-Ghashm_HJ.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R5-130.5 General works
spellingShingle	R5-130.5 General works Al-Ghashm, Abdulmlik Antiproliferative Effects Of The Orthosiphon Stamineus And Tualang Honey On Oral Squamous Cell Carcinoma And Human Osteosarcoma Cell Lines
description	Cancer is the fourth leading cause of death in Malaysia with almost 30,000 people contracting the disease annually. One of the important research fields is the beneficial effects of plants and natural products as effective chemotherapeutic agents. Honey exhibits a broad spectrum of therapeutic properties including antibacterial, antifungal, anti-inflammatory and moderate anticancer effects. It contains many biologically active compounds such as caffeic acid, caffeic acid phenethyl ester and flavonoid glycones which have been proven to exhibit inhibitory effect on tumor cell proliferation. Orthosiphon stamineus (O. stamineus) or ‘misai kucing’ is a popular traditional folk medicine used as medicinal herb for many centuries. It has many medicinal properties such as antioxidant activity, antifungal activity, diuretic activity, antidiabetic activity, anti-inflammatory activity. No previous study has been done to evaluate the effect of Tualang honey and O. stamineus on oral squamous cell carcinoma (OSCC) and human osteosarcoma (HOS). This study was aimed to verify the antiproliferative activity for several concentrations of Tualang honey, O. stamineus and mixed concentrations of honey and O. stamineus on OSCC and HOS cell lines. Several doses of Tualang honey (1% - 20%), several concentrations of O. stamineus (100μg/ml to 1mg/ml) and several mixed solutions of both were applied on OSCC and HOS cell culture for 3, 6, 12, 24, 48 and 72 hours.
format	Thesis
qualification_level	Master's degree
author	Al-Ghashm, Abdulmlik
author_facet	Al-Ghashm, Abdulmlik
author_sort	Al-Ghashm, Abdulmlik
title	Antiproliferative Effects Of The Orthosiphon Stamineus And Tualang Honey On Oral Squamous Cell Carcinoma And Human Osteosarcoma Cell Lines
title_short	Antiproliferative Effects Of The Orthosiphon Stamineus And Tualang Honey On Oral Squamous Cell Carcinoma And Human Osteosarcoma Cell Lines
title_full	Antiproliferative Effects Of The Orthosiphon Stamineus And Tualang Honey On Oral Squamous Cell Carcinoma And Human Osteosarcoma Cell Lines
title_fullStr	Antiproliferative Effects Of The Orthosiphon Stamineus And Tualang Honey On Oral Squamous Cell Carcinoma And Human Osteosarcoma Cell Lines
title_full_unstemmed	Antiproliferative Effects Of The Orthosiphon Stamineus And Tualang Honey On Oral Squamous Cell Carcinoma And Human Osteosarcoma Cell Lines
title_sort	antiproliferative effects of the orthosiphon stamineus and tualang honey on oral squamous cell carcinoma and human osteosarcoma cell lines
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2010
url	http://eprints.usm.my/42466/1/Abdulmlik_Al-Ghashm_HJ.pdf
_version_	1747821071183118336

Antiproliferative Effects Of The Orthosiphon Stamineus And Tualang Honey On Oral Squamous Cell Carcinoma And Human Osteosarcoma Cell Lines

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