Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation

Pelletised dosage forms can be prepared by different methods which, in general, are time consuming and labor intensive. The current study was carried out to assess the feasibility of preparing spherical pellets by sieving the wet powder mass followed by spheronisation. This method was compared with...

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Main Author:	Karim, Sabiha
Format:	Thesis
Language:	English
Published:	2011
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/42494/1/SABIHA_KARIM.pdf
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id	my-usm-ep.42494
record_format	uketd_dc
spelling	my-usm-ep.424942019-04-12T05:26:38Z Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation 2011-03 Karim, Sabiha RS1-441 Pharmacy and materia medica Pelletised dosage forms can be prepared by different methods which, in general, are time consuming and labor intensive. The current study was carried out to assess the feasibility of preparing spherical pellets by sieving the wet powder mass followed by spheronisation. This method was compared with extrusion-spheronisation process in terms of physical characteristics and in-vitro dissolution profile of the developed formulations. The fast release paracetamol pellets were comprised of, microcrystalline cellulose, lactose, crospovidone and polyvinyl pyrrolidone-K90. 2011-03 Thesis http://eprints.usm.my/42494/ http://eprints.usm.my/42494/1/SABIHA_KARIM.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Karim, Sabiha Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
description	Pelletised dosage forms can be prepared by different methods which, in general, are time consuming and labor intensive. The current study was carried out to assess the feasibility of preparing spherical pellets by sieving the wet powder mass followed by spheronisation. This method was compared with extrusion-spheronisation process in terms of physical characteristics and in-vitro dissolution profile of the developed formulations. The fast release paracetamol pellets were comprised of, microcrystalline cellulose, lactose, crospovidone and polyvinyl pyrrolidone-K90.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Karim, Sabiha
author_facet	Karim, Sabiha
author_sort	Karim, Sabiha
title	Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
title_short	Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
title_full	Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
title_fullStr	Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
title_full_unstemmed	Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation
title_sort	design and evaluation of multiparticulate systems prepared using sieving-spheronisation and extrusionspheronisation
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Farmasi
publishDate	2011
url	http://eprints.usm.my/42494/1/SABIHA_KARIM.pdf
_version_	1747821076559167488

Design And Evaluation Of Multiparticulate Systems Prepared Using Sieving-Spheronisation And Extrusionspheronisation

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