An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin

The potential of liposomal formulation as a drug delivery system for oral administration of poorly bioavailable drugs was studied using griseofulvin as the model drug. An extrusion technique using a self-assembled instrument was evaluated for nanosizing the liposomes. The particle size and size dist...

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Main Author:	Ong , Sandy Gim Ming
Format:	Thesis
Language:	English
Published:	2011
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/42530/1/SANDY_ONG_GIM_MING.pdf
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id	my-usm-ep.42530
record_format	uketd_dc
spelling	my-usm-ep.425302019-04-12T05:26:38Z An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin 2011-04 Ong , Sandy Gim Ming RS1-441 Pharmacy and materia medica The potential of liposomal formulation as a drug delivery system for oral administration of poorly bioavailable drugs was studied using griseofulvin as the model drug. An extrusion technique using a self-assembled instrument was evaluated for nanosizing the liposomes. The particle size and size distribution of liposomes produced was affected by various processing parameters. Nevertheless, the extrusion method was simple, reproducible and more effective compared to other size-reduction methods evaluated. 2011-04 Thesis http://eprints.usm.my/42530/ http://eprints.usm.my/42530/1/SANDY_ONG_GIM_MING.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Ong , Sandy Gim Ming An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin
description	The potential of liposomal formulation as a drug delivery system for oral administration of poorly bioavailable drugs was studied using griseofulvin as the model drug. An extrusion technique using a self-assembled instrument was evaluated for nanosizing the liposomes. The particle size and size distribution of liposomes produced was affected by various processing parameters. Nevertheless, the extrusion method was simple, reproducible and more effective compared to other size-reduction methods evaluated.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Ong , Sandy Gim Ming
author_facet	Ong , Sandy Gim Ming
author_sort	Ong , Sandy Gim Ming
title	An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin
title_short	An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin
title_full	An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin
title_fullStr	An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin
title_full_unstemmed	An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin
title_sort	investigation of liposomes for oral delivery of a poorly bioavailable model drug: griseofulvin
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Farmasi
publishDate	2011
url	http://eprints.usm.my/42530/1/SANDY_ONG_GIM_MING.pdf
_version_	1747821080222892032

An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin

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