Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)

Adherence to antihypertensive medications in general is not well documented in developing countries, and what is known is far from encouraging. Despite the effectiveness of antihypertensive treatment, medication adherence is often suboptimal in hypertensive Malaysian population. This retro-pro...

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Main Author:	Sundaram , Arunkumar
Format:	Thesis
Language:	English
Published:	2010
Subjects:	R5-130.5 General works
Online Access:	http://eprints.usm.my/42870/1/Arunkumar_Sundaram24.pdf
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id	my-usm-ep.42870
record_format	uketd_dc
spelling	my-usm-ep.428702019-04-12T05:26:52Z Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr) 2010-06 Sundaram , Arunkumar R5-130.5 General works Adherence to antihypertensive medications in general is not well documented in developing countries, and what is known is far from encouraging. Despite the effectiveness of antihypertensive treatment, medication adherence is often suboptimal in hypertensive Malaysian population. This retro-prospective cohort study aimed to assess the medication adherence, and factors affecting this. A cohort of 380 hypertensive patients was conveniently recruited from the outpatient hypertension clinic at Penang General Hospital, Malaysia. The Morisky self-report scale revealed that 51.3% patients (n=195) had poor adherence to prescribed antihypertensive medication. A Semistructured interview revealed forgetfulness due to a lack of symptoms; poor social support, medication side effects, and the perception that long-term medication may be addictive were principal factors of poor adherence to medication. The structural equation modelling (SEM), which identified the multivariate hypothesized predictors of poor adherence to medication, showed that a lack of self discipline, aversion towards medication, and a negative attitude towards medication in general negatively accounted for 75% of factors affecting medication adherence. 2010-06 Thesis http://eprints.usm.my/42870/ http://eprints.usm.my/42870/1/Arunkumar_Sundaram24.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Kesihatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R5-130.5 General works
spellingShingle	R5-130.5 General works Sundaram , Arunkumar Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)
description	Adherence to antihypertensive medications in general is not well documented in developing countries, and what is known is far from encouraging. Despite the effectiveness of antihypertensive treatment, medication adherence is often suboptimal in hypertensive Malaysian population. This retro-prospective cohort study aimed to assess the medication adherence, and factors affecting this. A cohort of 380 hypertensive patients was conveniently recruited from the outpatient hypertension clinic at Penang General Hospital, Malaysia. The Morisky self-report scale revealed that 51.3% patients (n=195) had poor adherence to prescribed antihypertensive medication. A Semistructured interview revealed forgetfulness due to a lack of symptoms; poor social support, medication side effects, and the perception that long-term medication may be addictive were principal factors of poor adherence to medication. The structural equation modelling (SEM), which identified the multivariate hypothesized predictors of poor adherence to medication, showed that a lack of self discipline, aversion towards medication, and a negative attitude towards medication in general negatively accounted for 75% of factors affecting medication adherence.
format	Thesis
qualification_level	Master's degree
author	Sundaram , Arunkumar
author_facet	Sundaram , Arunkumar
author_sort	Sundaram , Arunkumar
title	Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)
title_short	Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)
title_full	Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)
title_fullStr	Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)
title_full_unstemmed	Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)
title_sort	antioxidant status and the effect of tocotrienol-rich-fraction (trf) supplementation on the antioxidant enzymes and development of hypertension in spontaneously hypertensive rats (shr)
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Kesihatan
publishDate	2010
url	http://eprints.usm.my/42870/1/Arunkumar_Sundaram24.pdf
_version_	1747821116851748864

Antioxidant Status And The Effect Of Tocotrienol-Rich-Fraction (Trf) Supplementation On The Antioxidant Enzymes And Development Of Hypertension In Spontaneously Hypertensive Rats (Shr)

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