Anticancer Studies Of Koetjapic Acid Purified From Sandoricum Koetjape MERR

Colorectal cancer which involves the colon, rectum and the anal canal is the third most common malignancy worldwide. The disease is characterized by extensive angiogenesis and perturbation of a variety of oncogenes and tumor suppressor genes including, p53, Wnt, hypoxia, NF-кB, Notch, MAP kinase. Ta...

Full description

Saved in:
Bibliographic Details
Main Author: Nassar, Zeyad D.
Format: Thesis
Language:English
Published: 2011
Subjects:
Online Access:http://eprints.usm.my/42891/1/ZEYAD_D._NASSAR.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-usm-ep.42891
record_format uketd_dc
spelling my-usm-ep.428912019-04-12T05:26:39Z Anticancer Studies Of Koetjapic Acid Purified From Sandoricum Koetjape MERR 2011-02 Nassar, Zeyad D. RS1-441 Pharmacy and materia medica Colorectal cancer which involves the colon, rectum and the anal canal is the third most common malignancy worldwide. The disease is characterized by extensive angiogenesis and perturbation of a variety of oncogenes and tumor suppressor genes including, p53, Wnt, hypoxia, NF-кB, Notch, MAP kinase. Targeting one or more of these pathways increases the selectivity of the chemotherapeutic agents as these pathways are important for cancer cells growth and proliferation. Koetjapic acid is a naturally occurring seco-A-ring oleanene triterpene present in the Sandoricum koetjape species that grows in Malaysia and the Southeast Asian region. 2011-02 Thesis http://eprints.usm.my/42891/ http://eprints.usm.my/42891/1/ZEYAD_D._NASSAR.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic RS1-441 Pharmacy and materia medica
spellingShingle RS1-441 Pharmacy and materia medica
Nassar, Zeyad D.
Anticancer Studies Of Koetjapic Acid Purified From Sandoricum Koetjape MERR
description Colorectal cancer which involves the colon, rectum and the anal canal is the third most common malignancy worldwide. The disease is characterized by extensive angiogenesis and perturbation of a variety of oncogenes and tumor suppressor genes including, p53, Wnt, hypoxia, NF-кB, Notch, MAP kinase. Targeting one or more of these pathways increases the selectivity of the chemotherapeutic agents as these pathways are important for cancer cells growth and proliferation. Koetjapic acid is a naturally occurring seco-A-ring oleanene triterpene present in the Sandoricum koetjape species that grows in Malaysia and the Southeast Asian region.
format Thesis
qualification_level Master's degree
author Nassar, Zeyad D.
author_facet Nassar, Zeyad D.
author_sort Nassar, Zeyad D.
title Anticancer Studies Of Koetjapic Acid Purified From Sandoricum Koetjape MERR
title_short Anticancer Studies Of Koetjapic Acid Purified From Sandoricum Koetjape MERR
title_full Anticancer Studies Of Koetjapic Acid Purified From Sandoricum Koetjape MERR
title_fullStr Anticancer Studies Of Koetjapic Acid Purified From Sandoricum Koetjape MERR
title_full_unstemmed Anticancer Studies Of Koetjapic Acid Purified From Sandoricum Koetjape MERR
title_sort anticancer studies of koetjapic acid purified from sandoricum koetjape merr
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Farmasi
publishDate 2011
url http://eprints.usm.my/42891/1/ZEYAD_D._NASSAR.pdf
_version_ 1747821121029275648