In Vitro Anticancer Activity Guided Investigation Of The Phytochemicals Of Typhonium Flagelliforme (Lodd.) Blume (Araceae)

Typhonium flagelliforme (Lodd.) Blume is an indigenous plant of Malaysia used as a traditional herbal medicine to treat various types of cancer. In order to effectively understand its pharmacological action, safety and efficacy, it is essential to firstly identify and characterise its chemical const...

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Main Author:	Lai , Choon Sheen
Format:	Thesis
Language:	English
Published:	2010
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/42986/1/Lai_Choon_Sheen24.pdf
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id	my-usm-ep.42986
record_format	uketd_dc
spelling	my-usm-ep.429862019-04-12T05:26:51Z In Vitro Anticancer Activity Guided Investigation Of The Phytochemicals Of Typhonium Flagelliforme (Lodd.) Blume (Araceae) 2010-06 Lai , Choon Sheen RS1-441 Pharmacy and materia medica Typhonium flagelliforme (Lodd.) Blume is an indigenous plant of Malaysia used as a traditional herbal medicine to treat various types of cancer. In order to effectively understand its pharmacological action, safety and efficacy, it is essential to firstly identify and characterise its chemical constituents and their biological relevance to the healing effect of the plant. A suitable extraction methodology was carefully selected at the preliminary stage of this study. Three types of extraction methods with different modes of action, namely soxhlet, ultrasonic-assisted extraction and maceration methods were evaluated. The maceration method proved to be the most suitable extraction methodology for the purpose of this study with regard to the better activity and greater diversity of the chemical constituents obtained in the extract although the extraction yields were lower. The study also found that extraction carried out using non-polar solvents like hexane and dichloromethane is most suitable in obtaining the active chemical constituents. 2010-06 Thesis http://eprints.usm.my/42986/ http://eprints.usm.my/42986/1/Lai_Choon_Sheen24.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Penyelidikan Dadah dan Ubat-ubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Lai , Choon Sheen In Vitro Anticancer Activity Guided Investigation Of The Phytochemicals Of Typhonium Flagelliforme (Lodd.) Blume (Araceae)
description	Typhonium flagelliforme (Lodd.) Blume is an indigenous plant of Malaysia used as a traditional herbal medicine to treat various types of cancer. In order to effectively understand its pharmacological action, safety and efficacy, it is essential to firstly identify and characterise its chemical constituents and their biological relevance to the healing effect of the plant. A suitable extraction methodology was carefully selected at the preliminary stage of this study. Three types of extraction methods with different modes of action, namely soxhlet, ultrasonic-assisted extraction and maceration methods were evaluated. The maceration method proved to be the most suitable extraction methodology for the purpose of this study with regard to the better activity and greater diversity of the chemical constituents obtained in the extract although the extraction yields were lower. The study also found that extraction carried out using non-polar solvents like hexane and dichloromethane is most suitable in obtaining the active chemical constituents.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Lai , Choon Sheen
author_facet	Lai , Choon Sheen
author_sort	Lai , Choon Sheen
title	In Vitro Anticancer Activity Guided Investigation Of The Phytochemicals Of Typhonium Flagelliforme (Lodd.) Blume (Araceae)
title_short	In Vitro Anticancer Activity Guided Investigation Of The Phytochemicals Of Typhonium Flagelliforme (Lodd.) Blume (Araceae)
title_full	In Vitro Anticancer Activity Guided Investigation Of The Phytochemicals Of Typhonium Flagelliforme (Lodd.) Blume (Araceae)
title_fullStr	In Vitro Anticancer Activity Guided Investigation Of The Phytochemicals Of Typhonium Flagelliforme (Lodd.) Blume (Araceae)
title_full_unstemmed	In Vitro Anticancer Activity Guided Investigation Of The Phytochemicals Of Typhonium Flagelliforme (Lodd.) Blume (Araceae)
title_sort	in vitro anticancer activity guided investigation of the phytochemicals of typhonium flagelliforme (lodd.) blume (araceae)
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Penyelidikan Dadah dan Ubat-ubatan
publishDate	2010
url	http://eprints.usm.my/42986/1/Lai_Choon_Sheen24.pdf
_version_	1747821142541860864

In Vitro Anticancer Activity Guided Investigation Of The Phytochemicals Of Typhonium Flagelliforme (Lodd.) Blume (Araceae)

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