Preparation and characterization of collagen grafted poly(dimethyl siloxane) modified films for skin substitute applications.

Preparation and characterization of collagen grafted poly(dimethyl siloxane) modified films for skin substitute applications.

Poli(dimetil siloxana) (PDMS) filem yang berpusat diubah dengan menggunakan hidrogel dan kolagen untuk menghasilkan pelbagai jenis pengganti kulit. PHEMA (poli(hidroksietil metakrilat)) dan PAA (poli(asid akrilik)) digunakan melalui kaedah jujukan IPN (interpenetrating polymer networks) dan kaedah c...

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Main Author: Darvishi, Seyed Mahmood Rezaei
Format: Thesis
Language:English
Published: 2011
Subjects:
TN1-997 Mining engineering
Metallurgy
Online Access:http://eprints.usm.my/43007/1/Pages_from_PREPARATION_AND_CHARACTERIZATION_OF_COLLAGEN_GRAFTED_POLY%28DIMETHYL_SILOXANE%29_MODIFIED_FILMS_FOR_SKIN_SUBSTITUTE_APPLICATIONS.pdf
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spelling my-usm-ep.430072018-11-26T03:43:36Z Preparation and characterization of collagen grafted poly(dimethyl siloxane) modified films for skin substitute applications. 2011-02 Darvishi, Seyed Mahmood Rezaei TN1-997 Mining engineering. Metallurgy Poli(dimetil siloxana) (PDMS) filem yang berpusat diubah dengan menggunakan hidrogel dan kolagen untuk menghasilkan pelbagai jenis pengganti kulit. PHEMA (poli(hidroksietil metakrilat)) dan PAA (poli(asid akrilik)) digunakan melalui kaedah jujukan IPN (interpenetrating polymer networks) dan kaedah campuran bagi menghasilkan suatu kumpulan fungsi yang sesuai untuk menempatkan kologen pada lapisan luar PDMS, dalam usaha meningkatkan kebioserasian mereka. Kolagen (jenis I) dipautkan secara kovalen pada saput yang telah diubah suai dengan menggunakan kopel agen untuk mengaktifkan kumpulan hidroksil pada PHEMA dan karboksil pada PAA. Poly(dimethyl siloxane) (PDMS) based films were modified using hydrogels and collagen to produce different types of skin substitute. Poly(hydroxyethyl methacrylate) (PHEMA) and poly(acrylic acid)(PAA) were used via sequential method of interpenetrating polymer networks (IPNs) and blending methods to create suitable functional groups to immobilize collagen in outer layer of PDMS in order to enhance their biocompatibility. Collagen (type I) was covalently linked onto the modified films via coupling agent to activate the hydroxyl groups of PHEMA and the carboxylic groups of PAA. 2011-02 Thesis http://eprints.usm.my/43007/ http://eprints.usm.my/43007/1/Pages_from_PREPARATION_AND_CHARACTERIZATION_OF_COLLAGEN_GRAFTED_POLY%28DIMETHYL_SILOXANE%29_MODIFIED_FILMS_FOR_SKIN_SUBSTITUTE_APPLICATIONS.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Kejuruteraan Bahan & Sumber Mineral
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic TN1-997 Mining engineering
Metallurgy
spellingShingle TN1-997 Mining engineering
Metallurgy
Darvishi, Seyed Mahmood Rezaei
Preparation and characterization of collagen grafted poly(dimethyl siloxane) modified films for skin substitute applications.
description Poli(dimetil siloxana) (PDMS) filem yang berpusat diubah dengan menggunakan hidrogel dan kolagen untuk menghasilkan pelbagai jenis pengganti kulit. PHEMA (poli(hidroksietil metakrilat)) dan PAA (poli(asid akrilik)) digunakan melalui kaedah jujukan IPN (interpenetrating polymer networks) dan kaedah campuran bagi menghasilkan suatu kumpulan fungsi yang sesuai untuk menempatkan kologen pada lapisan luar PDMS, dalam usaha meningkatkan kebioserasian mereka. Kolagen (jenis I) dipautkan secara kovalen pada saput yang telah diubah suai dengan menggunakan kopel agen untuk mengaktifkan kumpulan hidroksil pada PHEMA dan karboksil pada PAA. Poly(dimethyl siloxane) (PDMS) based films were modified using hydrogels and collagen to produce different types of skin substitute. Poly(hydroxyethyl methacrylate) (PHEMA) and poly(acrylic acid)(PAA) were used via sequential method of interpenetrating polymer networks (IPNs) and blending methods to create suitable functional groups to immobilize collagen in outer layer of PDMS in order to enhance their biocompatibility. Collagen (type I) was covalently linked onto the modified films via coupling agent to activate the hydroxyl groups of PHEMA and the carboxylic groups of PAA.
format Thesis
qualification_name Doctor of Philosophy (PhD.)
qualification_level Doctorate
author Darvishi, Seyed Mahmood Rezaei
author_facet Darvishi, Seyed Mahmood Rezaei
author_sort Darvishi, Seyed Mahmood Rezaei
title Preparation and characterization of collagen grafted poly(dimethyl siloxane) modified films for skin substitute applications.
title_short Preparation and characterization of collagen grafted poly(dimethyl siloxane) modified films for skin substitute applications.
title_full Preparation and characterization of collagen grafted poly(dimethyl siloxane) modified films for skin substitute applications.
title_fullStr Preparation and characterization of collagen grafted poly(dimethyl siloxane) modified films for skin substitute applications.
title_full_unstemmed Preparation and characterization of collagen grafted poly(dimethyl siloxane) modified films for skin substitute applications.
title_sort preparation and characterization of collagen grafted poly(dimethyl siloxane) modified films for skin substitute applications.
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Kejuruteraan Bahan & Sumber Mineral
publishDate 2011
url http://eprints.usm.my/43007/1/Pages_from_PREPARATION_AND_CHARACTERIZATION_OF_COLLAGEN_GRAFTED_POLY%28DIMETHYL_SILOXANE%29_MODIFIED_FILMS_FOR_SKIN_SUBSTITUTE_APPLICATIONS.pdf
_version_ 1747821147184955392

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