The Effects Of Selenium And Tocotrienol Supplementation On The Muscle Contractile Properties, Fatigue, Emg And Antioxidant Status Of Gastrocnemius Muscle Of Trained And Untrained Rats

Exercise induces radical-mediated oxidative damage of skeletal muscle membranes which has been implicated in the fatigue process. Selenium (S) is an important component of cellular selenocompounds and is an integral component of glutathione Peroxidase (GPx), which catalyze the reduction of har...

Full description

Saved in:
Bibliographic Details
Main Author: Alwan, Mohand R.
Format: Thesis
Language:English
Published: 2009
Subjects:
Online Access:http://eprints.usm.my/43020/1/Mohand_R._Alwan24.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
id my-usm-ep.43020
record_format uketd_dc
spelling my-usm-ep.430202019-04-12T05:27:01Z The Effects Of Selenium And Tocotrienol Supplementation On The Muscle Contractile Properties, Fatigue, Emg And Antioxidant Status Of Gastrocnemius Muscle Of Trained And Untrained Rats 2009 Alwan, Mohand R. R5-920 Medicine (General) Exercise induces radical-mediated oxidative damage of skeletal muscle membranes which has been implicated in the fatigue process. Selenium (S) is an important component of cellular selenocompounds and is an integral component of glutathione Peroxidase (GPx), which catalyze the reduction of harmful peroxides. Tocotrienol (T) is a major chain breaking antioxidant that has been shown to reduce contraction mediated oxidative damage. We hypothesized that S and T supplementation would positively affect muscle contractile function and increase antioxidant enzymes activities during exercise. To test this postulate, were used sixty-four male Wistar-Kyoto rats at weight between 300-350g randomized into eight groups with eight rats per group rats these sample size was calculated using PS software based on comparing two means of superoxide dismutase (SOD). 2009 Thesis http://eprints.usm.my/43020/ http://eprints.usm.my/43020/1/Mohand_R._Alwan24.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R5-920 Medicine (General)
spellingShingle R5-920 Medicine (General)
Alwan, Mohand R.
The Effects Of Selenium And Tocotrienol Supplementation On The Muscle Contractile Properties, Fatigue, Emg And Antioxidant Status Of Gastrocnemius Muscle Of Trained And Untrained Rats
description Exercise induces radical-mediated oxidative damage of skeletal muscle membranes which has been implicated in the fatigue process. Selenium (S) is an important component of cellular selenocompounds and is an integral component of glutathione Peroxidase (GPx), which catalyze the reduction of harmful peroxides. Tocotrienol (T) is a major chain breaking antioxidant that has been shown to reduce contraction mediated oxidative damage. We hypothesized that S and T supplementation would positively affect muscle contractile function and increase antioxidant enzymes activities during exercise. To test this postulate, were used sixty-four male Wistar-Kyoto rats at weight between 300-350g randomized into eight groups with eight rats per group rats these sample size was calculated using PS software based on comparing two means of superoxide dismutase (SOD).
format Thesis
qualification_level Master's degree
author Alwan, Mohand R.
author_facet Alwan, Mohand R.
author_sort Alwan, Mohand R.
title The Effects Of Selenium And Tocotrienol Supplementation On The Muscle Contractile Properties, Fatigue, Emg And Antioxidant Status Of Gastrocnemius Muscle Of Trained And Untrained Rats
title_short The Effects Of Selenium And Tocotrienol Supplementation On The Muscle Contractile Properties, Fatigue, Emg And Antioxidant Status Of Gastrocnemius Muscle Of Trained And Untrained Rats
title_full The Effects Of Selenium And Tocotrienol Supplementation On The Muscle Contractile Properties, Fatigue, Emg And Antioxidant Status Of Gastrocnemius Muscle Of Trained And Untrained Rats
title_fullStr The Effects Of Selenium And Tocotrienol Supplementation On The Muscle Contractile Properties, Fatigue, Emg And Antioxidant Status Of Gastrocnemius Muscle Of Trained And Untrained Rats
title_full_unstemmed The Effects Of Selenium And Tocotrienol Supplementation On The Muscle Contractile Properties, Fatigue, Emg And Antioxidant Status Of Gastrocnemius Muscle Of Trained And Untrained Rats
title_sort effects of selenium and tocotrienol supplementation on the muscle contractile properties, fatigue, emg and antioxidant status of gastrocnemius muscle of trained and untrained rats
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Perubatan
publishDate 2009
url http://eprints.usm.my/43020/1/Mohand_R._Alwan24.pdf
_version_ 1747821150376820736