Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri

The aim of this study is to develop ADC calibration plot in diffusion MRI and to examine the signal intensity trend of MR-weighted T1-, T2-, proton density and Fluid Attenuated Inversion Recovery images as a function of time ranged from 1 hour to 60 days. Fresh human blood samples were drawn from fo...

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Main Author: Taib, Hartini Mohd
Format: Thesis
Language:English
Published: 2010
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Online Access:http://eprints.usm.my/43043/1/Nur_Hartini_Binti_Mohd_Taib24.pdf
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spelling my-usm-ep.430432019-04-12T05:26:53Z Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri 2010-05 Taib, Hartini Mohd R5-920 Medicine (General) The aim of this study is to develop ADC calibration plot in diffusion MRI and to examine the signal intensity trend of MR-weighted T1-, T2-, proton density and Fluid Attenuated Inversion Recovery images as a function of time ranged from 1 hour to 60 days. Fresh human blood samples were drawn from four volunteers and divided into 3 different categories namely, blood mixed with Citrate-Phosphate-Dextrose-Adenine (CPDA), blood mixed with thromboplastin and untreated blood as control. A set of T1WI, T2WI, PD, FLAIR and DWI were acquired using 1.0 Tesla MRI system (GE Signa Horizon LX) at Hospital Universiti Sains Malaysia. Measurements of the signal intensity for T1WI, T2WI, PD and FLAIR images were performed using GE ADW 2.0 Software. The reconstruction of the ADC maps and measurement of the ADC values for DWI were carried out using GE ADW 2.0 (Functool) Software. The study demonstrates that there is a significant trend displayed by all types of images. The trend was obviously exhibited in T1WI, PD and DWI. Generally the curves obtained can be divided into three parts. 2010-05 Thesis http://eprints.usm.my/43043/ http://eprints.usm.my/43043/1/Nur_Hartini_Binti_Mohd_Taib24.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R5-920 Medicine (General)
spellingShingle R5-920 Medicine (General)
Taib, Hartini Mohd
Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri
description The aim of this study is to develop ADC calibration plot in diffusion MRI and to examine the signal intensity trend of MR-weighted T1-, T2-, proton density and Fluid Attenuated Inversion Recovery images as a function of time ranged from 1 hour to 60 days. Fresh human blood samples were drawn from four volunteers and divided into 3 different categories namely, blood mixed with Citrate-Phosphate-Dextrose-Adenine (CPDA), blood mixed with thromboplastin and untreated blood as control. A set of T1WI, T2WI, PD, FLAIR and DWI were acquired using 1.0 Tesla MRI system (GE Signa Horizon LX) at Hospital Universiti Sains Malaysia. Measurements of the signal intensity for T1WI, T2WI, PD and FLAIR images were performed using GE ADW 2.0 Software. The reconstruction of the ADC maps and measurement of the ADC values for DWI were carried out using GE ADW 2.0 (Functool) Software. The study demonstrates that there is a significant trend displayed by all types of images. The trend was obviously exhibited in T1WI, PD and DWI. Generally the curves obtained can be divided into three parts.
format Thesis
qualification_level Master's degree
author Taib, Hartini Mohd
author_facet Taib, Hartini Mohd
author_sort Taib, Hartini Mohd
title Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri
title_short Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri
title_full Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri
title_fullStr Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri
title_full_unstemmed Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri
title_sort determination of apparent diffusion coefficient of blood at its various ages using the technique of diffusion mri
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Perubatan
publishDate 2010
url http://eprints.usm.my/43043/1/Nur_Hartini_Binti_Mohd_Taib24.pdf
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