Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena

Three species from the genus Homalomena, namely, H. pineodora, H. sagittifolia and H. coerulescens were chosen for this particular research since they have long been used in traditional medicine. The essential oils of the leaves and rhizomes of the three species were isolated by hydrodistillation an...

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Main Author:	., Abdul Hamid
Format:	Thesis
Language:	English
Published:	2011
Subjects:	QD1-999 Chemistry
Online Access:	http://eprints.usm.my/43189/1/ABDUL%20HAMID.pdf
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id	my-usm-ep.43189
record_format	uketd_dc
spelling	my-usm-ep.431892019-04-12T05:26:26Z Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena 2011-11 ., Abdul Hamid QD1-999 Chemistry Three species from the genus Homalomena, namely, H. pineodora, H. sagittifolia and H. coerulescens were chosen for this particular research since they have long been used in traditional medicine. The essential oils of the leaves and rhizomes of the three species were isolated by hydrodistillation and analyzed by capillary GC and GC-MS, utilizing two columns of different polarities. Isolation and purification of non-volatile phytochemicals were carried out using various solvent systems and chromatographic methods and their structures were determined by using spectroscopic methods such as FT-IR, one and two dimensional NMR experiments: 1H-NMR, 13C-NMR, DEPT 45, DEPT 90, DEPT 135, 1H-1H-COSY, 1H-1H-NOESY, 1H-13C-HMQC, 1H-13C-HMBC, GC-MS, DP-MS and LR-MS. The essential oils, crude extracts and some of the isolated compounds were assayed for biological activity (antibacterial, acetylcholinesterase enzyme inhibitory activity and anti-inflammatory activity) to evaluate their reported traditional uses. 2011-11 Thesis http://eprints.usm.my/43189/ http://eprints.usm.my/43189/1/ABDUL%20HAMID.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Kimia
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	QD1-999 Chemistry
spellingShingle	QD1-999 Chemistry ., Abdul Hamid Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena
description	Three species from the genus Homalomena, namely, H. pineodora, H. sagittifolia and H. coerulescens were chosen for this particular research since they have long been used in traditional medicine. The essential oils of the leaves and rhizomes of the three species were isolated by hydrodistillation and analyzed by capillary GC and GC-MS, utilizing two columns of different polarities. Isolation and purification of non-volatile phytochemicals were carried out using various solvent systems and chromatographic methods and their structures were determined by using spectroscopic methods such as FT-IR, one and two dimensional NMR experiments: 1H-NMR, 13C-NMR, DEPT 45, DEPT 90, DEPT 135, 1H-1H-COSY, 1H-1H-NOESY, 1H-13C-HMQC, 1H-13C-HMBC, GC-MS, DP-MS and LR-MS. The essential oils, crude extracts and some of the isolated compounds were assayed for biological activity (antibacterial, acetylcholinesterase enzyme inhibitory activity and anti-inflammatory activity) to evaluate their reported traditional uses.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	., Abdul Hamid
author_facet	., Abdul Hamid
author_sort	., Abdul Hamid
title	Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena
title_short	Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena
title_full	Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena
title_fullStr	Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena
title_full_unstemmed	Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena
title_sort	phytochemical and biological investigation on three species of the genus homalomena
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Kimia
publishDate	2011
url	http://eprints.usm.my/43189/1/ABDUL%20HAMID.pdf
_version_	1747821177295863808

Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena

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