Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae

Biotransformation of geraniol and nerol mediated by Saccharomyces cerevisiae was performed. Linalool and geraniol were mainly obtained from nerol using growing cells but only isomerisation to geraniol occurred using resting cells. Reductive biotransfomation of geraniol to citronellol was apparently...

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Main Author: Khor, Guat Kheng
Format: Thesis
Language:English
Published: 2011
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Online Access:http://eprints.usm.my/43357/1/KHOR%20GUAT%20KHENG.pdf
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spelling my-usm-ep.433572019-04-12T05:26:31Z Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae 2011-08 Khor, Guat Kheng TP1-1185 Chemical technology Biotransformation of geraniol and nerol mediated by Saccharomyces cerevisiae was performed. Linalool and geraniol were mainly obtained from nerol using growing cells but only isomerisation to geraniol occurred using resting cells. Reductive biotransfomation of geraniol to citronellol was apparently more effective with resting cells system. Combination of full factorial design with response surface methodology (RSM) was applied in order to evaluate the effects of cell density, substrate concentration and biotransformation time on product concentrations. The productivity increased proportionally with cell density. However, inhibition was observed at higher substrate concentrations. 2011-08 Thesis http://eprints.usm.my/43357/ http://eprints.usm.my/43357/1/KHOR%20GUAT%20KHENG.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Kejuteraan Kimia
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic TP1-1185 Chemical technology
spellingShingle TP1-1185 Chemical technology
Khor, Guat Kheng
Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae
description Biotransformation of geraniol and nerol mediated by Saccharomyces cerevisiae was performed. Linalool and geraniol were mainly obtained from nerol using growing cells but only isomerisation to geraniol occurred using resting cells. Reductive biotransfomation of geraniol to citronellol was apparently more effective with resting cells system. Combination of full factorial design with response surface methodology (RSM) was applied in order to evaluate the effects of cell density, substrate concentration and biotransformation time on product concentrations. The productivity increased proportionally with cell density. However, inhibition was observed at higher substrate concentrations.
format Thesis
qualification_level Master's degree
author Khor, Guat Kheng
author_facet Khor, Guat Kheng
author_sort Khor, Guat Kheng
title Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae
title_short Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae
title_full Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae
title_fullStr Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae
title_full_unstemmed Biotransformation Of Cis/Trans 3,7-Dimethyl-2,6-Octadien-1-Ol Mediated By Saccharomyces Cerevisiae
title_sort biotransformation of cis/trans 3,7-dimethyl-2,6-octadien-1-ol mediated by saccharomyces cerevisiae
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Kejuteraan Kimia
publishDate 2011
url http://eprints.usm.my/43357/1/KHOR%20GUAT%20KHENG.pdf
_version_ 1747821198803206144