Synthesis And Characterisation Of Mesoporous Hydroxyapatite Bioceramics
Mesoporous hydroxyapatite (HA) with smaller pore size in the nano range and with narrower pore size distribution is a better candidate to provide a more favourable drug release profile by exhibiting a more uniform and sustained release. This research was conducted to investigate the drug impregnatio...
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| Main Author: | |
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| Format: | Thesis |
| Language: | English |
| Published: |
2011
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| Subjects: | |
| Online Access: | http://eprints.usm.my/43364/1/LEW%20KIEN%20SENG.pdf |
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| Summary: | Mesoporous hydroxyapatite (HA) with smaller pore size in the nano range and with narrower pore size distribution is a better candidate to provide a more favourable drug release profile by exhibiting a more uniform and sustained release. This research was conducted to investigate the drug impregnation and release capability of mesoporous HA synthesised via a self-assembly mechanism between HA and cationic surfactant decyltrimethylammonium bromide (C10TAB) through a co-precipitation route. Different parameters such as pH-control technique, ageing duration, and water ratio were attempted during the synthesis to investigate their respective influence on the sorption properties. |
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