Synthesis And Characterisation Of Mesoporous Hydroxyapatite Bioceramics

Mesoporous hydroxyapatite (HA) with smaller pore size in the nano range and with narrower pore size distribution is a better candidate to provide a more favourable drug release profile by exhibiting a more uniform and sustained release. This research was conducted to investigate the drug impregnatio...

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Main Author: Lew, Kien Seng
Format: Thesis
Language:English
Published: 2011
Subjects:
Online Access:http://eprints.usm.my/43364/1/LEW%20KIEN%20SENG.pdf
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spelling my-usm-ep.433642019-04-12T05:26:31Z Synthesis And Characterisation Of Mesoporous Hydroxyapatite Bioceramics 2011-09 Lew, Kien Seng TN1-997 Mining engineering. Metallurgy Mesoporous hydroxyapatite (HA) with smaller pore size in the nano range and with narrower pore size distribution is a better candidate to provide a more favourable drug release profile by exhibiting a more uniform and sustained release. This research was conducted to investigate the drug impregnation and release capability of mesoporous HA synthesised via a self-assembly mechanism between HA and cationic surfactant decyltrimethylammonium bromide (C10TAB) through a co-precipitation route. Different parameters such as pH-control technique, ageing duration, and water ratio were attempted during the synthesis to investigate their respective influence on the sorption properties. 2011-09 Thesis http://eprints.usm.my/43364/ http://eprints.usm.my/43364/1/LEW%20KIEN%20SENG.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Kejuteraan Bahan & Sumber Mineral
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic TN1-997 Mining engineering
Metallurgy
spellingShingle TN1-997 Mining engineering
Metallurgy
Lew, Kien Seng
Synthesis And Characterisation Of Mesoporous Hydroxyapatite Bioceramics
description Mesoporous hydroxyapatite (HA) with smaller pore size in the nano range and with narrower pore size distribution is a better candidate to provide a more favourable drug release profile by exhibiting a more uniform and sustained release. This research was conducted to investigate the drug impregnation and release capability of mesoporous HA synthesised via a self-assembly mechanism between HA and cationic surfactant decyltrimethylammonium bromide (C10TAB) through a co-precipitation route. Different parameters such as pH-control technique, ageing duration, and water ratio were attempted during the synthesis to investigate their respective influence on the sorption properties.
format Thesis
qualification_level Master's degree
author Lew, Kien Seng
author_facet Lew, Kien Seng
author_sort Lew, Kien Seng
title Synthesis And Characterisation Of Mesoporous Hydroxyapatite Bioceramics
title_short Synthesis And Characterisation Of Mesoporous Hydroxyapatite Bioceramics
title_full Synthesis And Characterisation Of Mesoporous Hydroxyapatite Bioceramics
title_fullStr Synthesis And Characterisation Of Mesoporous Hydroxyapatite Bioceramics
title_full_unstemmed Synthesis And Characterisation Of Mesoporous Hydroxyapatite Bioceramics
title_sort synthesis and characterisation of mesoporous hydroxyapatite bioceramics
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Kejuteraan Bahan & Sumber Mineral
publishDate 2011
url http://eprints.usm.my/43364/1/LEW%20KIEN%20SENG.pdf
_version_ 1747821200503996416