Magnetic resonance imaging evaluation of the effect of tualang honey in breast tissue among postmenopausal breast cancer patient treated with anastrazole in HUSM

Objective: To investigate whether the combination treatment with Tualang honey (TH) influences the background parenchymal enhancement (BPE) at breast magnetic resonance imaging (MRI) in postmenopausal women with history of breast cancer treated with anastrozole. Methodology: A total of 22 patien...

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Main Author:	Nik Lah, Nik Shah Hizan
Format:	Thesis
Language:	English
Published:	2016
Subjects:	R Medicine (General)
Online Access:	http://eprints.usm.my/43499/1/Dr.%20Nik%20Shah%20Hizan-24%20pages.pdf
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id	my-usm-ep.43499
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spelling	my-usm-ep.434992019-04-12T05:25:32Z Magnetic resonance imaging evaluation of the effect of tualang honey in breast tissue among postmenopausal breast cancer patient treated with anastrazole in HUSM 2016 Nik Lah, Nik Shah Hizan R Medicine (General) Objective: To investigate whether the combination treatment with Tualang honey (TH) influences the background parenchymal enhancement (BPE) at breast magnetic resonance imaging (MRI) in postmenopausal women with history of breast cancer treated with anastrozole. Methodology: A total of 22 patients were recruited for both control (1 mg anastrozole daily) and intervention (1 mg anastrozole daily + 20 mg TH daily) groups from Oncology Clinic, Hospital USM, Kubang Kerian, Kelantan. Inclusive criteria included postmenopausal women with unilateral breast cancer stages I, II, or III, oestrogen receptor (ER) positive and/or progesterone receptor (PgR) positive and receiving anastrazole as treatment for or less a year were included. The BPE of contralateral breast before and 6 months after treatment was compared side by side using sign test. Results: A decrease in BPE was noted in 10% of women (p = 0.317) on anastrozole treatment, resulted in a category change of BPE from moderate to mild. The combination of anastrozole and TH treatment showed a decrease in BPE in 42% (p = 0.034) of postmenopausal breast cancer women. BPE decreased by one category of assessment in four women and by two categories of assessment in one woman. Conclusions: The combination of TH and anastrozole is more efficacious than anastrozole alone in decreasing breast BPE of ER-positive postmenopausal breast cancer women and thus reducing the risk of cancer recurrence. These findings further support the medicinal value of TH. 2016 Thesis http://eprints.usm.my/43499/ http://eprints.usm.my/43499/1/Dr.%20Nik%20Shah%20Hizan-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Nik Lah, Nik Shah Hizan Magnetic resonance imaging evaluation of the effect of tualang honey in breast tissue among postmenopausal breast cancer patient treated with anastrazole in HUSM
description	Objective: To investigate whether the combination treatment with Tualang honey (TH) influences the background parenchymal enhancement (BPE) at breast magnetic resonance imaging (MRI) in postmenopausal women with history of breast cancer treated with anastrozole. Methodology: A total of 22 patients were recruited for both control (1 mg anastrozole daily) and intervention (1 mg anastrozole daily + 20 mg TH daily) groups from Oncology Clinic, Hospital USM, Kubang Kerian, Kelantan. Inclusive criteria included postmenopausal women with unilateral breast cancer stages I, II, or III, oestrogen receptor (ER) positive and/or progesterone receptor (PgR) positive and receiving anastrazole as treatment for or less a year were included. The BPE of contralateral breast before and 6 months after treatment was compared side by side using sign test. Results: A decrease in BPE was noted in 10% of women (p = 0.317) on anastrozole treatment, resulted in a category change of BPE from moderate to mild. The combination of anastrozole and TH treatment showed a decrease in BPE in 42% (p = 0.034) of postmenopausal breast cancer women. BPE decreased by one category of assessment in four women and by two categories of assessment in one woman. Conclusions: The combination of TH and anastrozole is more efficacious than anastrozole alone in decreasing breast BPE of ER-positive postmenopausal breast cancer women and thus reducing the risk of cancer recurrence. These findings further support the medicinal value of TH.
format	Thesis
qualification_level	Master's degree
author	Nik Lah, Nik Shah Hizan
author_facet	Nik Lah, Nik Shah Hizan
author_sort	Nik Lah, Nik Shah Hizan
title	Magnetic resonance imaging evaluation of the effect of tualang honey in breast tissue among postmenopausal breast cancer patient treated with anastrazole in HUSM
title_short	Magnetic resonance imaging evaluation of the effect of tualang honey in breast tissue among postmenopausal breast cancer patient treated with anastrazole in HUSM
title_full	Magnetic resonance imaging evaluation of the effect of tualang honey in breast tissue among postmenopausal breast cancer patient treated with anastrazole in HUSM
title_fullStr	Magnetic resonance imaging evaluation of the effect of tualang honey in breast tissue among postmenopausal breast cancer patient treated with anastrazole in HUSM
title_full_unstemmed	Magnetic resonance imaging evaluation of the effect of tualang honey in breast tissue among postmenopausal breast cancer patient treated with anastrazole in HUSM
title_sort	magnetic resonance imaging evaluation of the effect of tualang honey in breast tissue among postmenopausal breast cancer patient treated with anastrazole in husm
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2016
url	http://eprints.usm.my/43499/1/Dr.%20Nik%20Shah%20Hizan-24%20pages.pdf
_version_	1747821227364319232

Magnetic resonance imaging evaluation of the effect of tualang honey in breast tissue among postmenopausal breast cancer patient treated with anastrazole in HUSM

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