The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells

Eurycoma longifolia Jack (Tongkat Ali) is one of the most popular traditional plants found in the tropical rainforest of Southeast Asia, especially in Malaysia and Indonesia. Although E. longifolia is widely used as traditional medicine, little is understood of the in vitro effect on Leydig cells;...

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Main Author: Ahmed, Nor Amira Khurshid
Format: Thesis
Language:English
Published: 2018
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Online Access:http://eprints.usm.my/43710/2/NOR%20AMIRA%20KHURSHID%20AHMED.pdf
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spelling my-usm-ep.437102019-04-12T05:24:47Z The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells 2018-07 Ahmed, Nor Amira Khurshid R735-854 Medical education. Medical schools. Research Eurycoma longifolia Jack (Tongkat Ali) is one of the most popular traditional plants found in the tropical rainforest of Southeast Asia, especially in Malaysia and Indonesia. Although E. longifolia is widely used as traditional medicine, little is understood of the in vitro effect on Leydig cells; the testosterone-producing cells. Therefore, the effect of a standardised E. longifolia extract (F2) and pure compound, eurycomanone (EN) on the productions of testosterone, estrogen and aromatase in mouse Leydig cells were determined in this study, whereby the Formestane (FM) was used as a positive control. The effect of F2, EN and FM on the cell viability was first determined using MTT assay. 2018-07 Thesis http://eprints.usm.my/43710/ http://eprints.usm.my/43710/2/NOR%20AMIRA%20KHURSHID%20AHMED.pdf application/pdf en public masters Universiti Sains Malaysia Institut Penyelidikan Perubatan Molekul
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R735-854 Medical education
Medical schools
Research
spellingShingle R735-854 Medical education
Medical schools
Research
Ahmed, Nor Amira Khurshid
The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells
description Eurycoma longifolia Jack (Tongkat Ali) is one of the most popular traditional plants found in the tropical rainforest of Southeast Asia, especially in Malaysia and Indonesia. Although E. longifolia is widely used as traditional medicine, little is understood of the in vitro effect on Leydig cells; the testosterone-producing cells. Therefore, the effect of a standardised E. longifolia extract (F2) and pure compound, eurycomanone (EN) on the productions of testosterone, estrogen and aromatase in mouse Leydig cells were determined in this study, whereby the Formestane (FM) was used as a positive control. The effect of F2, EN and FM on the cell viability was first determined using MTT assay.
format Thesis
qualification_level Master's degree
author Ahmed, Nor Amira Khurshid
author_facet Ahmed, Nor Amira Khurshid
author_sort Ahmed, Nor Amira Khurshid
title The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells
title_short The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells
title_full The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells
title_fullStr The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells
title_full_unstemmed The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells
title_sort effects of eurycoma longifolia extract and eurycomanone on the steroidogenesis in mouse leydig cells
granting_institution Universiti Sains Malaysia
granting_department Institut Penyelidikan Perubatan Molekul
publishDate 2018
url http://eprints.usm.my/43710/2/NOR%20AMIRA%20KHURSHID%20AHMED.pdf
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