The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells
Eurycoma longifolia Jack (Tongkat Ali) is one of the most popular traditional plants found in the tropical rainforest of Southeast Asia, especially in Malaysia and Indonesia. Although E. longifolia is widely used as traditional medicine, little is understood of the in vitro effect on Leydig cells;...
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my-usm-ep.437102019-04-12T05:24:47Z The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells 2018-07 Ahmed, Nor Amira Khurshid R735-854 Medical education. Medical schools. Research Eurycoma longifolia Jack (Tongkat Ali) is one of the most popular traditional plants found in the tropical rainforest of Southeast Asia, especially in Malaysia and Indonesia. Although E. longifolia is widely used as traditional medicine, little is understood of the in vitro effect on Leydig cells; the testosterone-producing cells. Therefore, the effect of a standardised E. longifolia extract (F2) and pure compound, eurycomanone (EN) on the productions of testosterone, estrogen and aromatase in mouse Leydig cells were determined in this study, whereby the Formestane (FM) was used as a positive control. The effect of F2, EN and FM on the cell viability was first determined using MTT assay. 2018-07 Thesis http://eprints.usm.my/43710/ http://eprints.usm.my/43710/2/NOR%20AMIRA%20KHURSHID%20AHMED.pdf application/pdf en public masters Universiti Sains Malaysia Institut Penyelidikan Perubatan Molekul |
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R735-854 Medical education Medical schools Research |
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R735-854 Medical education Medical schools Research Ahmed, Nor Amira Khurshid The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells |
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Eurycoma longifolia Jack (Tongkat Ali) is one of the most popular traditional plants found in the tropical rainforest of Southeast Asia, especially in Malaysia and
Indonesia. Although E. longifolia is widely used as traditional medicine, little is understood of the in vitro effect on Leydig cells; the testosterone-producing cells.
Therefore, the effect of a standardised E. longifolia extract (F2) and pure compound, eurycomanone (EN) on the productions of testosterone, estrogen and aromatase in
mouse Leydig cells were determined in this study, whereby the Formestane (FM) was used as a positive control. The effect of F2, EN and FM on the cell viability was first
determined using MTT assay. |
format |
Thesis |
qualification_level |
Master's degree |
author |
Ahmed, Nor Amira Khurshid |
author_facet |
Ahmed, Nor Amira Khurshid |
author_sort |
Ahmed, Nor Amira Khurshid |
title |
The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells |
title_short |
The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells |
title_full |
The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells |
title_fullStr |
The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells |
title_full_unstemmed |
The Effects Of Eurycoma Longifolia Extract And Eurycomanone On The Steroidogenesis In Mouse Leydig Cells |
title_sort |
effects of eurycoma longifolia extract and eurycomanone on the steroidogenesis in mouse leydig cells |
granting_institution |
Universiti Sains Malaysia |
granting_department |
Institut Penyelidikan Perubatan Molekul |
publishDate |
2018 |
url |
http://eprints.usm.my/43710/2/NOR%20AMIRA%20KHURSHID%20AHMED.pdf |
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1747821265461182464 |