Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial

Patients with End Stage Renal Disease (ESRD) require lifelong fluid replacement therapy or renal transplant. Almost 60-90 % haemodialysis patients are hypertensive. Studies aimed at elucidating the pathophysiology of hypertension among haemodialysis patients concluded that 90% cases resulted from so...

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Main Author:	Aftab, Raja Ahsan
Format:	Thesis
Language:	English
Published:	2018
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/43726/1/RAJA%20AHSAN%20AFTAB.pdf
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id	my-usm-ep.43726
record_format	uketd_dc
spelling	my-usm-ep.437262019-04-12T05:24:52Z Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial 2018-01 Aftab, Raja Ahsan RS1-441 Pharmacy and materia medica Patients with End Stage Renal Disease (ESRD) require lifelong fluid replacement therapy or renal transplant. Almost 60-90 % haemodialysis patients are hypertensive. Studies aimed at elucidating the pathophysiology of hypertension among haemodialysis patients concluded that 90% cases resulted from sodium and volume overload (volume-dependent), while the majority of the remaining cases have elevated renin activity (renin dependent), leading to renin dependent high blood pressure. Since there is a constant volume variation during dialysis session, there is a strong possibility for activation of Renin Angiotensin Aldosterone System (RAAS) during dialysis that causes high blood pressure even if they are post dialysis euvolemic. 2018-01 Thesis http://eprints.usm.my/43726/ http://eprints.usm.my/43726/1/RAJA%20AHSAN%20AFTAB.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Aftab, Raja Ahsan Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial
description	Patients with End Stage Renal Disease (ESRD) require lifelong fluid replacement therapy or renal transplant. Almost 60-90 % haemodialysis patients are hypertensive. Studies aimed at elucidating the pathophysiology of hypertension among haemodialysis patients concluded that 90% cases resulted from sodium and volume overload (volume-dependent), while the majority of the remaining cases have elevated renin activity (renin dependent), leading to renin dependent high blood pressure. Since there is a constant volume variation during dialysis session, there is a strong possibility for activation of Renin Angiotensin Aldosterone System (RAAS) during dialysis that causes high blood pressure even if they are post dialysis euvolemic.
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Aftab, Raja Ahsan
author_facet	Aftab, Raja Ahsan
author_sort	Aftab, Raja Ahsan
title	Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial
title_short	Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial
title_full	Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial
title_fullStr	Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial
title_full_unstemmed	Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial
title_sort	safety and efficacy of losartan (50 mg) in post dialysis euvolemic hypertensive patients: a single-blind randomized control trial
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Farmasi
publishDate	2018
url	http://eprints.usm.my/43726/1/RAJA%20AHSAN%20AFTAB.pdf
_version_	1747821268132954112

Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial

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