Explorative Study Of Adverse Drug Reactions And Drug-Resistant Tuberculosis Among Tuberculosis Patients In Hospital Pulau Pinang, Malaysia

Tuberculosis, an infectious disease caused by Mycobacterium tuberculosis claimed for human life throughout history today become second leading infectious diseases caused death after HIV-AIDS. Treatment of tuberculosis required combination of anti-tuberculosis drug. Anti-tuberculosis adverse dr...

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Main Author:	Kurniawati, Fivy
Format:	Thesis
Language:	English
Published:	2013
Subjects:	R5-920 Medicine (General)
Online Access:	http://eprints.usm.my/43800/1/Fivy%20Kurniawati24.pdf
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record_format	uketd_dc
spelling	my-usm-ep.438002019-04-12T05:26:18Z Explorative Study Of Adverse Drug Reactions And Drug-Resistant Tuberculosis Among Tuberculosis Patients In Hospital Pulau Pinang, Malaysia 2013-02 Kurniawati, Fivy R5-920 Medicine (General) Tuberculosis, an infectious disease caused by Mycobacterium tuberculosis claimed for human life throughout history today become second leading infectious diseases caused death after HIV-AIDS. Treatment of tuberculosis required combination of anti-tuberculosis drug. Anti-tuberculosis adverse drug reactions (ADRs) become important as longer use of these drugs. In addition to antituberculosis ADRs, the presence of tuberculosis bacteria that resistant to anti tuberculosis drug may complicate on tuberculosis treatment. This study was a retrospective cross-sectional observation study. Research subjects of this study were patients who were treated as active tuberculosis in Chest Clinic, Hospital Pulau Pinang, Malaysia. The aim of the study was to investigate anti-tuberculosis ADRs, drug-resistant tuberculosis (DR-TB), and all associate factors related to ADRs and DR-TB, also patients’ treatment clinical outcomes. Adverse drug reactions were detected from patients’ complains, clinical symptom, laboratory test result, and any other related information and DR-TB detected from patients’ sensitivity test result. Patients’ socio-demographic, medical history, tuberculosis diagnosis and treatment, clinical sign and symptom of ADRs, laboratory test result, sputum smear test, radiology test result, and other relevant information were collected. Obtained data then exported to excel and analyzed by using Statistical Package for Social Sciences (SPSS® version 15). 2013-02 Thesis http://eprints.usm.my/43800/ http://eprints.usm.my/43800/1/Fivy%20Kurniawati24.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R5-920 Medicine (General)
spellingShingle	R5-920 Medicine (General) Kurniawati, Fivy Explorative Study Of Adverse Drug Reactions And Drug-Resistant Tuberculosis Among Tuberculosis Patients In Hospital Pulau Pinang, Malaysia
description	Tuberculosis, an infectious disease caused by Mycobacterium tuberculosis claimed for human life throughout history today become second leading infectious diseases caused death after HIV-AIDS. Treatment of tuberculosis required combination of anti-tuberculosis drug. Anti-tuberculosis adverse drug reactions (ADRs) become important as longer use of these drugs. In addition to antituberculosis ADRs, the presence of tuberculosis bacteria that resistant to anti tuberculosis drug may complicate on tuberculosis treatment. This study was a retrospective cross-sectional observation study. Research subjects of this study were patients who were treated as active tuberculosis in Chest Clinic, Hospital Pulau Pinang, Malaysia. The aim of the study was to investigate anti-tuberculosis ADRs, drug-resistant tuberculosis (DR-TB), and all associate factors related to ADRs and DR-TB, also patients’ treatment clinical outcomes. Adverse drug reactions were detected from patients’ complains, clinical symptom, laboratory test result, and any other related information and DR-TB detected from patients’ sensitivity test result. Patients’ socio-demographic, medical history, tuberculosis diagnosis and treatment, clinical sign and symptom of ADRs, laboratory test result, sputum smear test, radiology test result, and other relevant information were collected. Obtained data then exported to excel and analyzed by using Statistical Package for Social Sciences (SPSS® version 15).
format	Thesis
qualification_level	Master's degree
author	Kurniawati, Fivy
author_facet	Kurniawati, Fivy
author_sort	Kurniawati, Fivy
title	Explorative Study Of Adverse Drug Reactions And Drug-Resistant Tuberculosis Among Tuberculosis Patients In Hospital Pulau Pinang, Malaysia
title_short	Explorative Study Of Adverse Drug Reactions And Drug-Resistant Tuberculosis Among Tuberculosis Patients In Hospital Pulau Pinang, Malaysia
title_full	Explorative Study Of Adverse Drug Reactions And Drug-Resistant Tuberculosis Among Tuberculosis Patients In Hospital Pulau Pinang, Malaysia
title_fullStr	Explorative Study Of Adverse Drug Reactions And Drug-Resistant Tuberculosis Among Tuberculosis Patients In Hospital Pulau Pinang, Malaysia
title_full_unstemmed	Explorative Study Of Adverse Drug Reactions And Drug-Resistant Tuberculosis Among Tuberculosis Patients In Hospital Pulau Pinang, Malaysia
title_sort	explorative study of adverse drug reactions and drug-resistant tuberculosis among tuberculosis patients in hospital pulau pinang, malaysia
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Farmasi
publishDate	2013
url	http://eprints.usm.my/43800/1/Fivy%20Kurniawati24.pdf
_version_	1747821282721792000

Explorative Study Of Adverse Drug Reactions And Drug-Resistant Tuberculosis Among Tuberculosis Patients In Hospital Pulau Pinang, Malaysia

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