Evaluation of visual acuity and macular thickness post focal laser with and without supplementary honey in diabetic macular oedema

Introduction Diabetic macular oedema (DMO) is a significant cause of vison loss in the diabetic patients. Laser is the standard treatment for DMO. Chronic inflammatory also has an important role in the pathogenesis of DMO. Tualang honey with anti-inflammatory and anti-oxidant properties has a po...

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Main Author:	Rahim, Raihan Abd
Format:	Thesis
Language:	English
Published:	2016
Subjects:	RE Ophthalmology
Online Access:	http://eprints.usm.my/43878/1/Dr.%20Raihan%20Abd%20Rahim-24%20pages.pdf
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spelling	my-usm-ep.438782019-04-12T05:25:32Z Evaluation of visual acuity and macular thickness post focal laser with and without supplementary honey in diabetic macular oedema 2016 Rahim, Raihan Abd RE Ophthalmology Introduction Diabetic macular oedema (DMO) is a significant cause of vison loss in the diabetic patients. Laser is the standard treatment for DMO. Chronic inflammatory also has an important role in the pathogenesis of DMO. Tualang honey with anti-inflammatory and anti-oxidant properties has a potential as an adjunct treatment for DMO. Objective To compare LogMAR best corrected visual acuity (BCVA) and central macular thickness (CMT) at 3 months post laser treatment between those with and without honey supplement in DMO. Methods A prospective randomized controlled study was conducted in Hospital Universiti Sains Malaysia between April 2013 and August 2015. Patient with clinically significant macular oedema (CSMO) was selected and was randomized by using randomised envelope technique into 2 groups; laser without honey group and laser with honey group. Patients were evaluated for LogMAR BCVA and CMT pre treatment and at 3 months post treatment. LogMAR BCVA was assessed using LogMAR chart and CMTwas measured using Heidelberg Spectralis OCT. Results A total of 52 patients were recruited (laser group without honey: 26 patients and laser with honey group: 26 patients) into this study. There was a significant improvement of mean LogMAR BCVA at 3 months post treatment in DMO patients treated with laser alone (p=0.002). However, there was no significant difference of the mean LogMAR BCVA in DMO patients treated with laser between those with and without honey supplement at 3 months post treatment (p=0.448). There was also no significant difference of mean CMT (p=0.881) at 3 months post laser treatment between those with and without honey supplement. There was no side effect of honey noted in patients consumed tualang honey. Conclusion Tualang honey used as adjunct with standard focal/grid laser has no additional improvement in both visual acuity and CMT compared to laser alone. 2016 Thesis http://eprints.usm.my/43878/ http://eprints.usm.my/43878/1/Dr.%20Raihan%20Abd%20Rahim-24%20pages.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RE Ophthalmology
spellingShingle	RE Ophthalmology Rahim, Raihan Abd Evaluation of visual acuity and macular thickness post focal laser with and without supplementary honey in diabetic macular oedema
description	Introduction Diabetic macular oedema (DMO) is a significant cause of vison loss in the diabetic patients. Laser is the standard treatment for DMO. Chronic inflammatory also has an important role in the pathogenesis of DMO. Tualang honey with anti-inflammatory and anti-oxidant properties has a potential as an adjunct treatment for DMO. Objective To compare LogMAR best corrected visual acuity (BCVA) and central macular thickness (CMT) at 3 months post laser treatment between those with and without honey supplement in DMO. Methods A prospective randomized controlled study was conducted in Hospital Universiti Sains Malaysia between April 2013 and August 2015. Patient with clinically significant macular oedema (CSMO) was selected and was randomized by using randomised envelope technique into 2 groups; laser without honey group and laser with honey group. Patients were evaluated for LogMAR BCVA and CMT pre treatment and at 3 months post treatment. LogMAR BCVA was assessed using LogMAR chart and CMTwas measured using Heidelberg Spectralis OCT. Results A total of 52 patients were recruited (laser group without honey: 26 patients and laser with honey group: 26 patients) into this study. There was a significant improvement of mean LogMAR BCVA at 3 months post treatment in DMO patients treated with laser alone (p=0.002). However, there was no significant difference of the mean LogMAR BCVA in DMO patients treated with laser between those with and without honey supplement at 3 months post treatment (p=0.448). There was also no significant difference of mean CMT (p=0.881) at 3 months post laser treatment between those with and without honey supplement. There was no side effect of honey noted in patients consumed tualang honey. Conclusion Tualang honey used as adjunct with standard focal/grid laser has no additional improvement in both visual acuity and CMT compared to laser alone.
format	Thesis
qualification_level	Master's degree
author	Rahim, Raihan Abd
author_facet	Rahim, Raihan Abd
author_sort	Rahim, Raihan Abd
title	Evaluation of visual acuity and macular thickness post focal laser with and without supplementary honey in diabetic macular oedema
title_short	Evaluation of visual acuity and macular thickness post focal laser with and without supplementary honey in diabetic macular oedema
title_full	Evaluation of visual acuity and macular thickness post focal laser with and without supplementary honey in diabetic macular oedema
title_fullStr	Evaluation of visual acuity and macular thickness post focal laser with and without supplementary honey in diabetic macular oedema
title_full_unstemmed	Evaluation of visual acuity and macular thickness post focal laser with and without supplementary honey in diabetic macular oedema
title_sort	evaluation of visual acuity and macular thickness post focal laser with and without supplementary honey in diabetic macular oedema
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Perubatan
publishDate	2016
url	http://eprints.usm.my/43878/1/Dr.%20Raihan%20Abd%20Rahim-24%20pages.pdf
_version_	1747821295206137856

Evaluation of visual acuity and macular thickness post focal laser with and without supplementary honey in diabetic macular oedema

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