Cytotoxic Effect, Anti-Proliferative And Cell Death Mechanism Of Latex C-Serum And Sub-Fractions Using Cell-Based Assay

Latex from Hevea brasiliensis, the natural rubber tree, has never been reported for folk medicinal use although highly regarded as an economic importance. Latex was thought to play a biological role in the plant defense system against microorganisms and insects. Due to scarce information available o...

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Main Author: Lam, Kit Lay
Format: Thesis
Language:English
Published: 2018
Subjects:
Online Access:http://eprints.usm.my/44120/1/LAM%20KIT%20LAY.pdf
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spelling my-usm-ep.441202019-04-18T01:56:18Z Cytotoxic Effect, Anti-Proliferative And Cell Death Mechanism Of Latex C-Serum And Sub-Fractions Using Cell-Based Assay 2018-03 Lam, Kit Lay R735-854 Medical education. Medical schools. Research Latex from Hevea brasiliensis, the natural rubber tree, has never been reported for folk medicinal use although highly regarded as an economic importance. Latex was thought to play a biological role in the plant defense system against microorganisms and insects. Due to scarce information available on the studies of its biological effects on mammalian system, cell viability assay using MTT, real-time PCR, cell cycle analysis and protein profiler analysis were used to evaluate the anticancer effects of and cell death pathway induced by whole C-serum (WC) and its fractions against the cancer-origin cell lines. 2018-03 Thesis http://eprints.usm.my/44120/ http://eprints.usm.my/44120/1/LAM%20KIT%20LAY.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Institut Penyelidikan Perubatan Molekul
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R735-854 Medical education
Medical schools
Research
spellingShingle R735-854 Medical education
Medical schools
Research
Lam, Kit Lay
Cytotoxic Effect, Anti-Proliferative And Cell Death Mechanism Of Latex C-Serum And Sub-Fractions Using Cell-Based Assay
description Latex from Hevea brasiliensis, the natural rubber tree, has never been reported for folk medicinal use although highly regarded as an economic importance. Latex was thought to play a biological role in the plant defense system against microorganisms and insects. Due to scarce information available on the studies of its biological effects on mammalian system, cell viability assay using MTT, real-time PCR, cell cycle analysis and protein profiler analysis were used to evaluate the anticancer effects of and cell death pathway induced by whole C-serum (WC) and its fractions against the cancer-origin cell lines.
format Thesis
qualification_name Doctor of Philosophy (PhD.)
qualification_level Doctorate
author Lam, Kit Lay
author_facet Lam, Kit Lay
author_sort Lam, Kit Lay
title Cytotoxic Effect, Anti-Proliferative And Cell Death Mechanism Of Latex C-Serum And Sub-Fractions Using Cell-Based Assay
title_short Cytotoxic Effect, Anti-Proliferative And Cell Death Mechanism Of Latex C-Serum And Sub-Fractions Using Cell-Based Assay
title_full Cytotoxic Effect, Anti-Proliferative And Cell Death Mechanism Of Latex C-Serum And Sub-Fractions Using Cell-Based Assay
title_fullStr Cytotoxic Effect, Anti-Proliferative And Cell Death Mechanism Of Latex C-Serum And Sub-Fractions Using Cell-Based Assay
title_full_unstemmed Cytotoxic Effect, Anti-Proliferative And Cell Death Mechanism Of Latex C-Serum And Sub-Fractions Using Cell-Based Assay
title_sort cytotoxic effect, anti-proliferative and cell death mechanism of latex c-serum and sub-fractions using cell-based assay
granting_institution Universiti Sains Malaysia
granting_department Institut Penyelidikan Perubatan Molekul
publishDate 2018
url http://eprints.usm.my/44120/1/LAM%20KIT%20LAY.pdf
_version_ 1747821331385155584