Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel
The leaves of Mitragyna speciosa Korth (M. speciosa), commonly known as ketum in Malaysia, have been widely used to treat common illnesses such as intestinal infections, muscle pain, cough, diarrhea, diabetes, hypertension and to improve blood circulation. Nevertheless, there are growing concerns ab...
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2018
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my-usm-ep.441332019-04-18T06:52:47Z Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel 2018-04 Tay, Yea Lu RS200-201 Pharmaceutical dosage forms The leaves of Mitragyna speciosa Korth (M. speciosa), commonly known as ketum in Malaysia, have been widely used to treat common illnesses such as intestinal infections, muscle pain, cough, diarrhea, diabetes, hypertension and to improve blood circulation. Nevertheless, there are growing concerns about the safety and abuse or misuse potentials of the plant which exhibits addictive effects. The safety profile of the plant is not fully elucidated. The human ether-a-go-go-related gene 1 (hERG1) encodes the pore-forming subunit underlying cardiac rapidly delayed rectifier potassium current (IKr). 2018-04 Thesis http://eprints.usm.my/44133/ http://eprints.usm.my/44133/1/TAY%20YEA%20LU.pdf application/pdf en public phd doctoral Universiti Sains Malaysia Institut Farmaseutikal & Nutraseutikal Malaysia |
| institution |
Universiti Sains Malaysia |
| collection |
USM Institutional Repository |
| language |
English |
| topic |
RS200-201 Pharmaceutical dosage forms |
| spellingShingle |
RS200-201 Pharmaceutical dosage forms Tay, Yea Lu Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel |
| description |
The leaves of Mitragyna speciosa Korth (M. speciosa), commonly known as ketum in Malaysia, have been widely used to treat common illnesses such as intestinal infections, muscle pain, cough, diarrhea, diabetes, hypertension and to improve blood circulation. Nevertheless, there are growing concerns about the safety and abuse or misuse potentials of the plant which exhibits addictive effects. The safety profile of the plant is not fully elucidated. The human ether-a-go-go-related gene 1 (hERG1) encodes the pore-forming subunit underlying cardiac rapidly delayed rectifier potassium current (IKr). |
| format |
Thesis |
| qualification_name |
Doctor of Philosophy (PhD.) |
| qualification_level |
Doctorate |
| author |
Tay, Yea Lu |
| author_facet |
Tay, Yea Lu |
| author_sort |
Tay, Yea Lu |
| title |
Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel |
| title_short |
Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel |
| title_full |
Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel |
| title_fullStr |
Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel |
| title_full_unstemmed |
Molecular Mechanisms Of Mitragynine Inhibition On Herg1a/1b Channel |
| title_sort |
molecular mechanisms of mitragynine inhibition on herg1a/1b channel |
| granting_institution |
Universiti Sains Malaysia |
| granting_department |
Institut Farmaseutikal & Nutraseutikal Malaysia |
| publishDate |
2018 |
| url |
http://eprints.usm.my/44133/1/TAY%20YEA%20LU.pdf |
| _version_ |
1747821333863989248 |