Formulation And Evaluation Of Self-Emulsifying Drug Delivery Systems Of Azithromycin To Enhance Its Penetration Through The Epithelial Tight Junctions

Azithromycin (AZM) is a macrolide antibiotic used for the treatment of a number of bacterial infections. It is known to have a low oral bioavailability (37 %) due to its relatively high molecular weight, incomplete solubility and/or poor intestinal permeability, which is potentially restricting its...

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Main Author:	Assi, Reem Abou
Format:	Thesis
Language:	English
Published:	2018
Subjects:	RS1-441 Pharmacy and materia medica
Online Access:	http://eprints.usm.my/44259/1/REEM%20ABOU%20ASSI.pdf
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id	my-usm-ep.44259
record_format	uketd_dc
spelling	my-usm-ep.442592019-05-06T01:39:00Z Formulation And Evaluation Of Self-Emulsifying Drug Delivery Systems Of Azithromycin To Enhance Its Penetration Through The Epithelial Tight Junctions 2018-03 Assi, Reem Abou RS1-441 Pharmacy and materia medica Azithromycin (AZM) is a macrolide antibiotic used for the treatment of a number of bacterial infections. It is known to have a low oral bioavailability (37 %) due to its relatively high molecular weight, incomplete solubility and/or poor intestinal permeability, which is potentially restricting its intestinal absorption. To overcome these drawbacks liquid and solid self-emulsifying drug delivery systems (L-SEDDs and S-SEDDs) of AZM were prepared in an attempt to enhance its solubility, and altering its cellular penetration, which might improve its oral bioavailability. 2018-03 Thesis http://eprints.usm.my/44259/ http://eprints.usm.my/44259/1/REEM%20ABOU%20ASSI.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	RS1-441 Pharmacy and materia medica
spellingShingle	RS1-441 Pharmacy and materia medica Assi, Reem Abou Formulation And Evaluation Of Self-Emulsifying Drug Delivery Systems Of Azithromycin To Enhance Its Penetration Through The Epithelial Tight Junctions
description	Azithromycin (AZM) is a macrolide antibiotic used for the treatment of a number of bacterial infections. It is known to have a low oral bioavailability (37 %) due to its relatively high molecular weight, incomplete solubility and/or poor intestinal permeability, which is potentially restricting its intestinal absorption. To overcome these drawbacks liquid and solid self-emulsifying drug delivery systems (L-SEDDs and S-SEDDs) of AZM were prepared in an attempt to enhance its solubility, and altering its cellular penetration, which might improve its oral bioavailability.
format	Thesis
qualification_level	Master's degree
author	Assi, Reem Abou
author_facet	Assi, Reem Abou
author_sort	Assi, Reem Abou
title	Formulation And Evaluation Of Self-Emulsifying Drug Delivery Systems Of Azithromycin To Enhance Its Penetration Through The Epithelial Tight Junctions
title_short	Formulation And Evaluation Of Self-Emulsifying Drug Delivery Systems Of Azithromycin To Enhance Its Penetration Through The Epithelial Tight Junctions
title_full	Formulation And Evaluation Of Self-Emulsifying Drug Delivery Systems Of Azithromycin To Enhance Its Penetration Through The Epithelial Tight Junctions
title_fullStr	Formulation And Evaluation Of Self-Emulsifying Drug Delivery Systems Of Azithromycin To Enhance Its Penetration Through The Epithelial Tight Junctions
title_full_unstemmed	Formulation And Evaluation Of Self-Emulsifying Drug Delivery Systems Of Azithromycin To Enhance Its Penetration Through The Epithelial Tight Junctions
title_sort	formulation and evaluation of self-emulsifying drug delivery systems of azithromycin to enhance its penetration through the epithelial tight junctions
granting_institution	Universiti Sains Malaysia
granting_department	Pusat Pengajian Sains Farmasi
publishDate	2018
url	http://eprints.usm.my/44259/1/REEM%20ABOU%20ASSI.pdf
_version_	1747821349459460096

Formulation And Evaluation Of Self-Emulsifying Drug Delivery Systems Of Azithromycin To Enhance Its Penetration Through The Epithelial Tight Junctions

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